, 2007 目的探讨量化非特异性相互作用在特异性选择素．配体分子相互作用中的贡献。方法利用光镊技术，对牛血清白蛋白（Bovine serum albumin，BSA）封闭的玻璃小球间的非特异性作用进行了系统测量，得出不同加载率下的断裂力以及不同外力作用下的寿命分布。结果实验结果表明，非特异性作用同样表现出断裂力随加载率增加而增大的趋势。在较低加载率下，非特异性断裂力与选择素-配体特异性断裂力大小、增大趋势基本一致；随着加载率增加，二者的差别逐渐显著，前者的断裂力增加速率远低于后者。同样外力作用下 ...
孙淦云, 龙勉, 章燕, 李宁
core
[The moderating effect of smartphone addiction on the relationship between social skills and anxiety among left-behind secondary school students]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiLiu JX +6 more
europepmc +1 more source
, 2012 受体一配体之间的相互作用可介导细胞间通信。依据受体、配体所受约束不同,可以将其相互作用划分为两类:一是三维相互作用,即受体或配体中至少有一种为可溶性状态;二是二维相互作用,即受体与配体均锚定于某个表面(如细胞膜表面),只有当锚定表面靠近到一定距离,其相互作用才可能发生。生理环境下,这两种作用都存在,相同的受体和配体就会产生竞争作用。在炎症反应发生时,锚定于白细胞表面的L选择素会在某些因子(比如fMLP,IL-8)的刺激下发生水解,形成可溶性的L选择素,从而与未发生水解的L选择素共同竞争配体 ...
吕守芹, 龙勉, 章燕, 彭爽
core
[<i>Miao</i> medicine <i>Sidaxue</i> regulates macrophage polarization and alleviates synovial inflammation in collagen-induced arthritis rats by inhibiting HIF-1α/PDK1-mediated glycolytic reprogramming]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoShen W +6 more
europepmc +1 more source
[<i>Qihuang Jianpi Zishen</i> Granule ameliorates renal injury in patients with systemic lupus erythematosus by regulating immunometabolic reprogramming of macrophages]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoQian A +5 more
europepmc +1 more source
[Development of high-performance chromatographic materials and their application in herbalome research since 2020]. [PDF]
Se PuFeng J +8 more
europepmc +1 more source
[Hepatocellular carcinoma-derived lactate-mediated histone H3K18 lactylation modifies S100A2 transcription to promote proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHuang L, Shao Y, Zhou W, He J.
europepmc +1 more source
[Social isolation induces social avoidance in mice: the mediating role of the medial prefrontal cortex glutamatergic neurons]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYuan Q, Zhang D, Wang J, Song H.
europepmc +1 more source
[A cross-subject stress recognition method integrating bidirectional cross-modal multi-path fusion and adaptive adversarial learning]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiWang P, Zhu M, Chou Y, Wei X, Liu S.
europepmc +1 more source