The Value of Interaction in Data Intelligence
CoRR, 2018 This paper was first submitted to CHI2019 on 21 Sept. 2018. Version 2 was submitted to CHI2023 on 10 Sept. 2022. Although it was not accepted in either case, the author believes that it may still be a useful contribution to the field of HCI. Version 3 includes the correction of a typo (in Eq. 3) identified by a CHI2023 reviewer. Version 4 was submitted
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Modelling online community constructs through interaction data: A learning analytics based Approach. [PDF]
Educ Inf Technol (Dordr), 2022 Çakiroğlu Ü, Kahyar S.
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
TEAD inhibitors synergize with MEK, SHP2 and mTOR inhibitors in NF1 and NF2 cell lines
microPublication BiologyNeurofibromatosis type 1 (NF1) and NF2-related Schwannomatosis (NF2-SWN) are both inherited syndromes characterized by Schwann cell tumors. NF1 tumors harbor activated Ras/MEK/ERK, while NF2-SWN tumors harbor activated mechanosignaling pathways ...
Yang Yang +3 more
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
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microPublication BiologyProper centrosome duplication requires precise regulation of ZYG-1. CK2-mediated phosphorylation of ZYG-1 contributes to this process by controlling ZYG-1 stability and centrosome number.
Amber Christian +5 more
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Arabidopsis Transcription Regulatory Factor Domain/Domain Interaction Analysis Tool-Liquid/Liquid Phase Separation, Oligomerization, GO Analysis: A Toolkit for Interaction Data-Based Domain Analysis. [PDF]
Genes (Basel), 2023 Kang JE +6 more
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
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The P granule antibody KT3 recognizes epitopes in both PGL-1 and PGL-3
microPublication BiologyThe KT3 antibody is a commercially available antibody that recognizes the P granule protein PGL-3 (Takeda et al., 2008). Using immunostaining and western blotting of purified peptide fragments, we show that KT3 recognizes both PGL-3 and its paralog PGL-1,
Brennan M Danlasky +5 more
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3D reconstruction of genomic regions from sparse interaction data. [PDF]
NAR Genom Bioinform, 2021 Mendieta-Esteban J +4 more
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