Results 81 to 90 of about 73,785 (231)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Classroom Interaction and Language Learning in CLIL contexts

CLIL Journal of Innovation and Research in Plurilingual and Pluricultural Education, 2018
This article provides a comprehensive overview of the key aspects of classroom interaction in L2 and CLIL contexts and its effects on students’ academic and language development in such educational settings.
Natalia Evnitskaya
doaj   +1 more source

Assessing interactional competence

, 2022
Die Entwicklung von Sprechkompetenz wird weithin als ein zentraler Bestandteil des Fremdsprachenerwerbs angesehen. Es kann jedoch hinterfragt werden, ob aktuell geläufige Konzeptionen dieses Begriffs der Komplexität des Konstruktes gerecht werden.
openaire   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

What authentic data tell us about pupils’ interactional competence: A video-based interdisciplinary study

Ricerche di Pedagogia e Didattica
This article introduces the Special Issue presenting the first findings of the Italian project ChICaS (Children's Interactional Competence at School: Conversational Social Norms, Forms of Participation, and Language Structures), a PRIN (Progetto di ...
Piera Margutti, Elisa De Roberto, Rosa Pugliese, Elisa Rossi, Daniela Veronesi   +4 more
doaj   +1 more source

In the heat of the sequence: Interactional features preceding walkouts from argumentative talk [PDF]

, 2001
This article examines complaint sequences that terminate with one party’s walking out, unilaterally, on the other. The analysis of three such extended sequences, using the Conversation Analytic approach, reveals interactional parallels among them.
Dersley, I., Wootton, A.J.
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Explaining cross-cultural pragmatic findings: moving from politeness maxims to sociopragmatic interactional principles (SIPs) [PDF]

, 2003
This paper focuses on how culture can be treated as an explanatory variable in cross-cultural pragmatic studies. It starts with a review of pragmatic maxims [Grice, H. Paul, 1989. Logic and Conversation. William James Lectures, 1967. (Reprinted in Grice,
Brown, Canary, Chen, Fraser, Gazdar, Grice, Gu, Gudykunst, Helen Spencer-Oatey, House, Kim, Kim, Leech, Lorenzo-Dus, Schwartz, Sifianou, Spencer-Oatey, Spencer-Oatey, Spencer-Oatey, Thomas, Thomas, Watts, Wenying Jiang, Wierzbicka   +23 more
core   +1 more source

Symbolic Competence in Interaction: Mutuality, Memory, and Resistance in a Peer Tutoring Context

L2 Journal, 2016
Symbolic competence (Kramsch, 2009, 2011) has been proposed as a crucial addition to world language learning, as it enables a language learner to negotiate the complex symbolism of words, expressions, and discursive events from the target culture in ...
Michele Back
doaj  

LEARNING TO SAY GRACE

Social Interaction, 2018
Based on a detailed analysis of four naturally occurring dinner-table conversations video-recorded over a period of three weeks, this study uses longitudinal Conversation Analysis to track an outsider's growing involvement in the family ritual of praying
Tim Greer
doaj   +1 more source