Results 71 to 80 of about 73,785 (231)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Prevalent Use of Global System of Mobile Phone (GSM) for Communication in Nigeria

Nordic Journal of African Studies, 2005
The main issue investigated in this study was what became of the interpersonal profile of the sampled population in view of their prevalent use of GSM phone, a communication enhancing technological device that came with the millennium encroachment of ...
O. S. Elegbeleye
doaj   +1 more source

Atomic Dynamics in Liquids with Competing Interactions

Physical Review Letters, 2004
The influence of the type of atomic interaction on the atomic dynamics is studied for liquid Na(x)Sn(1-x) (x = 0.9, 0.77, 0.57, 0.5, 0.33) alloys by cold neutron inelastic scattering. The dispersions obtained from the longitudinal current correlation function J(l)(Q,omega) show clear evidence for the dependence of the dynamics on the type of ...
Jahn, S., Suck, J.
openaire   +6 more sources

Managing rapport in talk: using rapport sensitive incidents to explore the motivational concerns underlying the management of relations [PDF]

, 2002
This paper focuses on the motivational concerns that underlie the management of relations. In linguistics, the management of relations has been discussed extensively within politeness theory, and so the paper starts by identifying four key issues of ...
Brown, Chen, Fraser, Gao, Goffman, Goffman, Gu, Gudykunst, Helen Spencer-Oatey∗, Ide, Kasper, Kasper, Kasper, Leech, Mao, Markus, Matsumoto, Morisaki, Pavlidou, Scollon, Spencer-Oatey, Spencer-Oatey, Ting-Toomey, Watts, Watzlawick   +24 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Simulation-Based Learning in Training Contexts [PDF]

Educaţia 21
This article examines how professionals preparing to become trainers for Școala de Valori/The School of Values association engage in simulation-based learning.
Silvia Bogdan, Natalia-Maria Durușa
doaj   +1 more source

Fluency in dialogue: Turn‐taking behavior shapes perceived fluency in native and nonnative speech

, 2020
Fluency is an important part of research on second language learning, but most research on language proficiency typically has not included oral fluency as part of interaction, even though natural communication usually occurs in conversations. The present
Bosker, H., De Jong, N., Van Os, M.
core   +1 more source

Storytelling and story-acting: co-construction in action [PDF]

, 2017
In the light of sustained interest in the potential value of young children’s narrative play, this paper examines Vivian Gussin Paley’s (1990) approach to storytelling and story-acting, in this case with three to five year-olds.
Cremin, Teresa, Faulkner, Dorothy, Flewitt, Rosie, Kucirkova, Natalia, Swann, Joan   +4 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Developing sexual competence? Exploring strategies for the provision of effective sexualities and relationships education [PDF]

, 2008
School-based sexualities and relationships education (SRE) offers one of the most promising means of improving young people's sexual health through developing 'sexual competence'. In the absence of evidence on whether the term holds the same meanings for
Aggleton P., Fine M., Giddens A., Harding J., Hirst J., Hirst J., Ingham R., Julia Hirst, Kippax S., Kvale S., Measor L., Measor L., Morris R. W., Smith D. E., Trudell B. N., Westwood J.   +15 more
core   +1 more source