Results 61 to 70 of about 5,935 (298)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

FLUCTUATIONS AND PATTERN FORMATION IN FLUIDS WITH COMPETING INTERACTIONS [PDF]

Collective Phenomena in Macroscopic Systems, 2007
One of the most interesting phenomena in the soft-matter realm consists in the spontaneous formation of super-molecular structures (microphases) in condition of thermodynamic equilibrium. A simple mechanism responsible for this self-organization or pattern formation is based on the competition between attractive and repulsive forces with different ...
A. Imperio, D. Pini, L. Reatto
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Teachers’ Classroom Interactional Competence: An Analysis in Micro-Contexts of Teacher-Class Interaction

Altralang Journal
Creating learning opportunities depends to a greater extent on classroom interaction, in which learning is maximised when teachers demonstrate classroom interactional competence (CIC).
Asma AZIZ, Samira ARAR
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Prevalent Use of Global System of Mobile Phone (GSM) for Communication in Nigeria

Nordic Journal of African Studies, 2005
The main issue investigated in this study was what became of the interpersonal profile of the sampled population in view of their prevalent use of GSM phone, a communication enhancing technological device that came with the millennium encroachment of ...
O. S. Elegbeleye
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Improving Communicative Competence through Synchronous Communication in Computer-Supported Collaborative Learning Environments: A Systematic Review

Education Sciences, 2018
Computer-supported collaborative learning facilitates the extension of second language acquisition into social practice. Studies on its achievement effects speak directly to the pedagogical notion of treating communicative practice in synchronous ...
Xi Huang
doaj   +1 more source

Classroom Interactional Competence in a Japanese Elementary English Classroom [PDF]

, 2018
The study examined classroom interactional competence in an elementary English classroom in Japan, seeking to illuminate the nature of interactions between pupils and instructors, a Japanese homeroom teacher (HRT) and a native-speaker assistant language ...
大橋, 由美, Ohashi, Yumi
core   +1 more source

Development of interactional competence in Spanish-language service learning

, 2021
This study analyzes the development of Interactional Competence by two advanced-level undergraduate Spanish students in the service-learning context where they volunteered as Spanish-language instructors in either an adult basic education class or an ESL
Burt, Erika Linnea
core   +1 more source