Results 61 to 70 of about 73,785 (231)
Fluid of discs with competing interactions [PDF]
Molecular Physics, 2011 We study within the framework of density functional theory the behaviour of a two dimensional fluid with a competing attraction at short distances and repulsion at longer distance in addition to a hard-core. The soft part of the interaction is treated by a first-order thermodynamic perturbation theory, which for a homogeneous bulk fluid predicts that ...
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The ontology of signs as linguistic and non-linguistic entities: a cognitive perspective [PDF]
, 2003 It is argued that the traditional philosophical/linguistic analysis of semiotic phe-nomena is based on the false epistemological assumption that linguistic and non-linguistic entities possess different ontologies.
Kravchenko, Prof. A.V.
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Altralang JournalCreating learning opportunities depends to a greater extent on classroom interaction, in which learning is maximised when teachers demonstrate classroom interactional competence (CIC).
Asma AZIZ, Samira ARAR
doaj +1 more source
Metaphoric competence and communicative language ability [PDF]
, 2006 Recent developments in cognitive linguistics have highlighted the importance as well as the ubiquity of metaphor in language. Despite this, the ability of second language learners to use metaphors is often still not seen as a core ability. In this paper,
Littlemore, Jeannette, Low, Graham
core
Editorial. Clinical pragmatics: an emergentist perspective [PDF]
, 2005 [First Paragraph] Clinical pragmatics has been a major growth area in clinical linguistics and speech and language pathology over the past two decades. Its scope is vast: if we define pragmatics in broad terms, there are no communicative disorders which ...
Perkins, Michael R
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Education Sciences, 2018 Computer-supported collaborative learning facilitates the extension of second language acquisition into social practice. Studies on its achievement effects speak directly to the pedagogical notion of treating communicative practice in synchronous ...
Xi Huang
doaj +1 more source