Results 51 to 60 of about 73,785 (231)

Culture as Non-Consensus: Exploring Coherence Among Native Speakers’ Perceptions of German Expressions of Affection [PDF]

open access: yes, 2020
From early in their learning experience, foreign language (FL) learners at American universities explore socio-cultural connotations that, it is argued, are signified by FL words.
Fichtner, Friederike
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Cross-Cultural Pragmatics of Interactional Competence

open access: yesBaltic Journal of English Language, Literature and Culture, 2011
Interactional competence involves knowledge of the relation between language forms and the social contexts in which they are applied. The paper aims at focusing on the concept of interactional competence within the framework of cross-cultural pragmatics.
Gunta Roziņa
doaj  

Embodiment, Semantics and Social Action: The Case of Object-Transfer in L2 Classroom Interaction

open access: yesFrontiers in Communication, 2021
Using conversation analysis and usage-based linguistics, I focus on a beginning L2 user in an ESL classroom and trace his use of a “family of expressions” which, from the perspective of linguistic theory, are instantiations of either the ditransitive ...
S. W. Eskildsen
doaj   +1 more source

Sinking or swimming in the New Zealand mainstream: Four young Asian learners in a new languaculture [PDF]

open access: yes, 2009
New Zealand schools are increasingly diverse in terms of language and culture, and many immigrant school children are faced with the ‘languacultural’ (Agar, 1994) challenge of learning not only a new language but a new culture of learning – to learn new ...
Barnard, Roger
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Series of Conversation Analysis Based Pedagogical Activities for Increasing Interactional Awareness

open access: yesAraştırma Temelli Etkinlik Dergisi, 2019
This article presents a series of activities that are informed by research on conversation analysis and used for increasing the EFL [English as a Foreign Language] learners’ awareness of interactional mechanisms of English language.
Ufuk Balaman, Nilüfer Can Daşkın
doaj   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Development of Interactional Competence in a Virtual Exchange Setting: Focus on Diversification of Participatory Actions

open access: yesInternational Journal of Qualitative Methods
Virtual exchange (VE) projects create environments providing VE participants with L2 development opportunities. This study examines the affordances of VEs with a particular emphasis on how participants find opportunities for developing their ...
Semih Ekin
doaj   +1 more source

Dynamic Assessment and Microgenetic Development of EFL Teachers’ Classroom Interactional Competence [PDF]

open access: yesTeaching English Language, 2015
Teachers’ capability in shaping learner contributions (SLC), as a part of Classroom Interactional Competence (CIC), has been evidenced to play a key role in opening up precious opportunities for learners’ involvement, and consequently learning. Yet, very
Mahmood Moradian   +2 more
doaj   +1 more source

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