Results 31 to 40 of about 94,289 (211)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Research advances of intercellular cell adhesion molecule-1 in IgA nephropathy

Linchuang shenzangbing zazhi, 2022
As a 90 kDa member of immunoglobulin superfamily in adhesion molecules， intercellular cell adhesion molecule-1 （ICAM-1） is the most widely studied of five ICAM molecules.
Wang Shan-shan, Zhang Xue-qin, Lu Chen
doaj  

Association of Intercellular Adhesion Molecule 1 (ICAM1) with Diabetes and Diabetic Nephropathy

Frontiers in Endocrinology, 2013
Diabetes and diabetic nephropathy are complex diseases affected by genetic and environmental factors. Identification of the susceptibility genes and investigation of their roles may provide useful information for better understanding of the pathogenesis ...
Harvest F Gu, Jun eMa, Karolin T Gu, Kerstin eBrismar   +3 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Soluble adhesion molecules and angiotensin-converting enzyme in dementia

Neurobiology of Disease, 2007
We aimed to determine plasma and cerebrospinal fluid (CSF) levels of angiotensin-converting enzyme (ACE) and the soluble forms of intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1) and platelet endothelial cell ...
Henrietta M. Nielsen, Elisabet Londos, Lennart Minthon, Sabina M. Janciauskiene   +3 more
doaj   +1 more source

Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells. [PDF]

PLoS ONE, 2012
Incorporation of intercellular adhesion molecule 1 (ICAM-1) into HIV-1 particles is known to markedly enhance the virus binding and infection of cells expressing lymphocyte function-associated antigen-1 (LFA-1). At the same time, ICAM-1 has been reported
Naoyuki Kondo, Gregory B Melikyan
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Angiogenesis outcomes of metformin utilization in diabetes mellitus: a systematic review and meta-analysis

Journal of the Pakistan Medical Association
Objective: To review relevant literature regarding the role of metformin in angiogenesis among diabetic patients. Method: The systematic review and meta-analysis conducted from May to September 2022, and comprised search on Medline, ScienceDirect ...
Primasitha Maharani Harsoyo, Hanestya Oky Hermawan, Arisvia Sukma Hariftyani, Farah Aisha Shabrina, Anisya Dinda Paramitha, Saskia Ratna Desita, Yudi Her Oktaviono   +6 more
doaj   +1 more source

Intercellular adhesion molecule-4 and CD36 are implicated in the abnormal adhesiveness of sickle cell SAD mouse erythrocytes to endothelium

Haematologica, 2010
Background Abnormal adhesiveness of red blood cells to endothelium has been implicated in vaso-occlusive crisis of sickle cell disease. The present study examined whether the SAD mouse model exhibits the same abnormalities of red blood cell adhesion as ...
Marie-Marcelle Trinh-Trang-Tan, Camilo Vilela-Lamego, Julien Picot, Marie-Paule Wautier, Jean-Pierre Cartron   +4 more
doaj   +1 more source