Uncertainty Quantification and Sensitivity Analysis for the Electrical Impedance Spectroscopy of Changes to Intercellular Junctions Induced by Cold Atmospheric Plasma [PDF]
Molecules, 2022 The influence of pertinent parameters of a Cole-Cole model in the impedimetric assessment of cell-monolayers was investigated with respect to the significance of their individual contribution.
Jie Zhuang +5 more
doaj +2 more sources
Treponema pallidum Disrupts VE-Cadherin Intercellular Junctions and Traverses Endothelial Barriers Using a Cholesterol-Dependent Mechanism [PDF]
Frontiers in Microbiology, 2021 Treponema pallidum subspecies pallidum, the causative agent of syphilis, traverses the vascular endothelium to gain access to underlying tissue sites. Herein, we investigate the mechanisms associated with T.
Karen V. Lithgow +6 more
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Phosphatase regulation of intercellular junctions. [PDF]
Tissue Barriers, 2013 Intercellular junctions represent the key contact points and sites of communication between neighboring cells. Assembly of these junctions is absolutely essential for the structural integrity of cell monolayers, tissues and organs. Disruption of junctions can have severe consequences such as diarrhea, edema and sepsis, and contribute to the development
McCole DF.
europepmc +6 more sources
Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α–DSG2 signaling [PDF]
Experimental and Molecular Medicines Circulating tumor cell (CTC) clusters, key in metastasis, rely on intercellular junctions for stability. However, the specific mechanisms governing intercellular connections within CTC clusters and the strategy targeting intercellular junctions to ...
Jueyao Zou +14 more
doaj +2 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Many respiratory pathogens compromise epithelial barrier function during lung infection by disrupting intercellular junctions, such as adherens junctions and tight junctions, that maintain intercellular integrity.
Devons Mo +7 more
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Overview of junctional complexes during mammalian early embryonic development
Frontiers in Endocrinology, 2023 Cell-cell junctions form strong intercellular connections and mediate communication between blastomeres during preimplantation embryonic development and thus are crucial for cell integrity, polarity, cell fate specification and morphogenesis.
Ceren Canse, Ecem Yildirim, Aylin Yaba
doaj +1 more source
Cell Reports, 2020 Summary: Influenza A virus (IAV) primarily infects the airway and alveolar epithelial cells and disrupts the intercellular junctions, leading to increased paracellular permeability.
Tao Ruan +6 more
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Learning theories reveal loss of pancreatic electrical connectivity in diabetes as an adaptive response [PDF]
, 2013 Cells of almost all solid tissues are connected with gap junctions which permit the direct transfer of ions and small molecules, integral to regulating coordinated function in the tissue.
Goel, Pranay, Mehta, Anita
core +6 more sources
Molecular Diffusion through Cyanobacterial Septal Junctions
mBio, 2017 Heterocyst-forming cyanobacteria grow as filaments in which intercellular molecular exchange takes place. During the differentiation of N2-fixing heterocysts, regulators are transferred between cells.
Mercedes Nieves-Morión +2 more
doaj +1 more source
Intercellular Junctions: Actin the PARt [PDF]
Current Biology, 2008 Several distinct polarity complexes participate in the assembly of intercellular junctions. Two studies showing that some of the same polarity complexes are essential regulators of continued junctional integrity lead to a new appreciation of the relationships between assembly and maintenance of intercellular junctions and highlight unappreciated roles ...
Shen, Le, Turner, Jerrold R.
openaire +2 more sources