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Intercellular Junctions in the Differentiating Rat Otocyst

Annals of Otology, Rhinology & Laryngology, 1979
Intercellular junctions between cells of the rat otocyst on the 12th day of gestation were studied using lanthanum tracer and freeze-fracture techniques. At the luminal surface, the intercellular space is closed by a series of tight junctions. Gap junctions are also present between cells both within and below the luminal junctional complex.
K M, Khan, W F, Marovitz
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Intercellular Junctions in the Organ of Corti

Annals of Otology, Rhinology & Laryngology, 1978
The intercellular junctions between adjacent supporting cells and between apposed hair and supporting cells in the organ of Corti of cat and human were studied. At the endolymphatic surface, the intercellular space was closed by a series of tight junctions (zonula occludens), whereas there were no tight junctions at the basilar membrane surface of the ...
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Assessment of Gap Junctional Intercellular Communication

Current Protocols in Toxicology, 2009
AbstractGap junctions are important plasma membrane organelles through which most cells in normal tissues communicate with each other. They exist in two neighboring cells and each cell contributes half of the structure. One gap junction consists of two hexameric connexons that dock with each other to create a channel. Six of the basic subunits referred
James E, Klaunig, Yuhui, Shi
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Isolation of intercellular junctions

1992
Abstract Early electron microscopic studies revealed the existence of a number of distinct types of intercellular junctions. Specific physiological properties of a cell or tissue could often be correlated with the presence of a particular type of junction, suggesting very different functions for each type.
Elliot L Hertzberg   +3 more
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Single-channel currents of an intercellular junction

Nature, 1985
We have used a double whole-cell patch-clamp system to make the first quantitative recordings of the single-channel current from an intercellular junction, presumably a gap junction. The junctional channel has various conductance states and discriminates poorly between cations and anions. It seems to change slowly from one conductance state to another.
J, Neyton, A, Trautmann
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Structure and Function of Intercellular Junctions

1974
Publisher Summary Intercellular junctions are specialized regions of contact between the apposed plasma membranes of adjacent cells, and recent evidence suggests that they are essential for the development of multicellular organisms. They provide the structural means for groups of cells to interact in certain defined ways, and thereby enable them to ...
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Structure of gap junction intercellular channels

Current Opinion in Structural Biology, 1996
Gap junctions are formed by a multigene family of polytopic membrane channel proteins, connexins, that have four hydrophobic transmembrane domains and their N and C termini located on the cytoplasmic membrane face. The C-terminal tail plays important roles in channel regulation by pH and phosphorylation.
M, Yeager, B J, Nicholson
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Protective effect of corticosteroids on intercellular junction

Experimental Cell Research, 1977
Abstract Actions of adrenocortical hormones on intercellular communication in salivary gland cells of Chironomus plumosus were studied by means of electrophysiological measurements. Glucocorticoids have an effect maintaining junctional communication, while mineralocorticoids have an effect blocking it.
K, Suzuki, S, Higashino
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Intercellular junctions in nerve-free hydra

Cell and Tissue Research, 1980
Epithelial cells of nerve-free hydra contain septate and gap junctions. In thin sections the gap junctions are characterized by a gap of 3-4 nm. Freeze-fracture demonstrates the presence of septate junctions and two further types of structures: (i) the "E-type" or "inverted" gap junctions with particles in an "enplaque conformation appearing as a ...
Lepault, J.   +2 more
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The Structure and Function of Intercellular Junctions in Cancer

1976
Publisher Summary Intercellular junctions are a set of structurally complex membrane components that are incorporated into the general plasma membrane at the sites of close cell-to-cell apposition. The primary function of some types of junctions, such as gap junctions, remains obscure; this is unfortunate because a considerable body of information on
R S, Weinstein, F B, Merk, J, Alroy
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