Quantitative Determination of Gap Junction Intercellular Communication Using Flow Cytometric Measurement of Fluorescent Dye Transfer [PDF]
Mina Holm Juul+3 more
openalex +1 more source
Structure and Function of Intercellular Junctions in Human Cervical and Vaginal Mucosal Epithelia1
Caitlin D. Blaskewicz+2 more
semanticscholar +1 more source
This study reveals histone lactylation as a metabolic‐epigenetic regulator countering cellular senescence and skeletal muscle aging. Reduced lactylation impairs cell cycle, DNA repair and proteostasis pathways, while exercise restores glycolytic activity and lactylation levels, preserving muscle function.
Fanju Meng+16 more
wiley +1 more source
Introductory Commentary on Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hematopoietic Stem Cells Ploemacher R. Et Al [PDF]
Joel S. Greenberger, Armand Keating
openalex +1 more source
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang+11 more
wiley +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source
Increase of VEGF and Fibronectin expression and ultrastructural alterations of intercellular junctions in a swab negative patient after SARS-COV-2 infection. [PDF]
Simioni C+6 more
europepmc +1 more source
Exosomal Thrombospondin-1 Disrupts the Integrity of Endothelial Intercellular Junctions to Facilitate Breast Cancer Cell Metastasis. [PDF]
Cen J+7 more
europepmc +1 more source
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang+5 more
wiley +1 more source
Early Radiation-Induced Changes in Lung Tissue and Intercellular Junctions: Implications for Tissue Repair and Fibrosis. [PDF]
Karetnikova ES+3 more
europepmc +1 more source