Results 31 to 40 of about 925,963 (223)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Topological Interference Management for MIMO Interference Broadcast Channels
IEEE Access, 2019 In this paper, we investigate the topological interference management (TIM) for MIMO interference broadcast channels (IBC) under the fixed topology, where only topology information is needed to cancel the inter-cell interference (ICI).
Wei Liu +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
On interference and non-interference in the SMEFT
Journal of High Energy Physics, 2018 We discuss interference in the limit m^W2/s→0 $$ {\widehat{m}}_W^2/s\to 0 $$ in the Standard Model Effective Field Theory (SMEFT). Dimension six operators that contribute to ψ¯ψ→ψ¯′1ψ′2ψ¯′3ψ′4 $$ \overline{\psi}\psi \to \overline{\psi}{\prime}_1\psi ...
Andreas Helset, Michael Trott
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Écriture et discours critique : Une interférence préjudiciable à l'oeuvre ?
, 1991 Basfao Kacem. Écriture et discours critique : Une interférence préjudiciable à l'oeuvre ?. In: Horizons Maghrébins - Le droit à la mémoire, N°17, 1991. La perception critique du texte maghrébin de langue française. pp.
Basfao, Kacem
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Journal of High Energy Physics, 2021 The Standard Model Effective Field Theory (SMEFT) offers a powerful theoretical framework for parameterizing the low-energy effects of heavy new particles with masses far above the scale of electroweak symmetry breaking.
Anne Mareike Galda +2 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source