Results 51 to 60 of about 925,963 (223)

Interférence stripping et noyau composé dans la réaction 16O(d, p1) (Ed < 1,2 MeV)

, 1968
The 16O( p1)17O* (871 keV) angular distributions are analysed by stripping-compound effect calculation near Ed ~ 0.450, 0.650 and 1 MeV resonances reported previously.Les distributions angulaires de la réaction 16O(d, p 1)17O* (871 keV) sont analysées ...
Nguyen Van Sen, M. Yaker, N. Longequeue, H. Beaumevieille, Tsan Ung Chan   +4 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Impact de l’apprentissage précoce de l’anglais sur les compétences orales en français langue étrangère en Algérie : cas des élèves de la troisième année primaire

Langues & Cultures
Cet article s’inscrit dans une perspective sociolinguistique, il se propose d’étudier les effets de l’introduction de l’anglais, à l’école primaire en Algérie, sur le développement des compétences orales en français langue étrangère.
Mohamed HATTAB, Abdelli KANDSI
doaj   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Blind Interference Alignment in Two-Cell Z Interference MIMO Channel

IEEE Access, 2017
This paper proposes a blind interference alignment (BIA) scheme in two-cell Z interference multiple-input multiple-output channel where the cell edge user equipment (UE) of the first cell is interfered by the base station of the second cell during ...
Xiao Chen, Zaichen Zhang, Lili Zheng, Liang Wu, Jian Dang, Pen-Shun Lu, Chen Sun   +6 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Interférence des métabolites de l’éthylène glycol sur le dosage ampérométrique du lactate sur analyseur ABL 825

, 2010
Cas clinique : Un homme de 86 ans est retrouvé inconscient à son domicile sans notion d’intoxication. À son admission, il présente une acidose (pH = 7,24) associée à une hyperlactacidémie à 26 mmol/L sur ABL 825® Radiometer,
Mustapha Moulsma, François Parant, Antony Citterio-Quentin, Laurence Chardon, Fabien Tissier   +4 more
core   +1 more source