Results 51 to 60 of about 1,646,245 (299)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A MEG Study on the Processing of Time and Quantity: Parietal Overlap but Functional Divergence

open access: yesFrontiers in Psychology, 2019
A common magnitude system for the processing of time and numerosity, supported by areas in the posterior parietal cortex, has been proposed by some authors. The present study aims to investigate possible intersections between the neural processing of non-
Elena Salillas   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Hot Carrier Degradation in Si n-MOSFETs at Cryogenic Temperatures

open access: yesIEEE Journal of the Electron Devices Society
This study experimentally investigated hot carrier degradation (HCD) in Si-MOSFETs at cryogenic temperatures. Stress was applied to the devices at 4 K and 300 K, followed by temperature-dependent characterization from 4 K to 300 K to evaluate the ...
Shunsuke Shitakata   +6 more
doaj   +1 more source

Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes

open access: yesFrontiers in Immunology, 2018
Francisella tularensis is a remarkably infectious facultative intracellular bacterium of macrophages that causes tularemia. Early evasion of host immune responses contributes to the success of F. tularensis as a pathogen. F.
Ky V. Hoang   +6 more
doaj   +1 more source

Instability of interfaces in the antiferromagnetic XXZ chain at zero temperature

open access: yes, 2003
For the antiferromagnetic, highly anisotropic XZ and XXZ quantum spin chains, we impose periodic boundary conditions on chains with an odd number of sites to force an interface (or kink) into the chain.
Datta, Nilanjana, Kennedy, Tom
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Admittance spectroscopy of boron phosphide heterostructures grown by plasma enhanced chemical vapor deposition on silicon substrates

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics
The study of BP layers and BP/n-Si heterojunctions formed by plasma enhanced chemical deposition on n-Si substrates has been carried out at a temperature of 350 °C using diborane and phosphine.
Baranov Artem   +5 more
doaj   +1 more source

Automatic Parameter Extraction Technique for MOS Structures by C-V Characterization Including the Effects of Interface States

open access: yesMeasurement Science Review, 2016
An automatic MOS structure parameter extraction algorithm accounting for quantum effects has been developed and applied in the semiconductor device analyzer Agilent B1500A.
Ryazantsev D. V., Grudtsov V. P.
doaj   +1 more source

Decoding Inner Speech Using Electrocorticography: Progress and Challenges Toward a Speech Prosthesis

open access: yesFrontiers in Neuroscience, 2018
Certain brain disorders resulting from brainstem infarcts, traumatic brain injury, cerebral palsy, stroke, and amyotrophic lateral sclerosis, limit verbal communication despite the patient being fully aware.
Stephanie Martin   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy