Results 61 to 70 of about 6,332,703 (315)

United States Bureau of Mines Bulletin 439 [PDF]

open access: yes, 1941
From Purpose of Report: "This paper is based partly upon the authors' observations and partly upon studies of tunnel driving; these cover essentially all types of tunnels in various parts of the United States during the past 25 years.
Harrington, D.   +1 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Revista INTERFACE [PDF]

open access: yes, 2019
Revista INTERFACE - Edição ...
adminccsa
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

An interface configuration experiment on USML-1 [PDF]

open access: yes, 1993
Experiments were carried out for exotic'' rotationally symmetric containers aboard the first NASA United States Microgravity Laboratory Space Shuttle flight (USML-1).
Concus, P. (Lawrence Berkeley Lab., CA (United States))   +2 more
core  

Analysis of the EEG Rhythms Based on the Empirical Mode Decomposition During Motor Imagery When Using a Lower-Limb Exoskeleton. A Case Study

open access: yesFrontiers in Neurorobotics, 2020
The use of brain-machine interfaces in combination with robotic exoskeletons is usually based on the analysis of the changes in power that some brain rhythms experience during a motion event.
Mario Ortiz   +4 more
doaj   +1 more source

Conformational States of Polymers Adsorbed on Interfaces [PDF]

open access: yesPolymer Journal, 1991
Adsorbed layer thickness (t) of several dilute polymeric systems were measured by ellipsometry. For physically adsorbed homopolymers, t scales as M0.5 and M0.4 in theta and good solvents, respectively. Conformational change from “mushroom” to “brush” were observed for a terminally attached polyelectrolyte by adjusting electrostatic “excluded volume ...
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

DEPLOYMENT OF A DEEP LEARNING MODEL TO ASSIST PATHOLOGISTS WITH DONOR KIDNEY BIOPSY EVALUATION

open access: yesJournal of Pathology Informatics, 2022
Joseph Gaut   +5 more
doaj   +1 more source

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