Results 61 to 70 of about 3,381 (218)
Coherent transfer of topological interface states
Optics Express, 2020 We demonstrate the controlled coherent transfer of topological interface states in a one-dimensional non-Hermitian chain of interacting Bose-Einstein condensates. The topological protection stems from a spatially patterned pump in an open-dissipative system.
Comaron P. +2 more
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in Neurorobotics, 2020 The use of brain-machine interfaces in combination with robotic exoskeletons is usually based on the analysis of the changes in power that some brain rhythms experience during a motion event.
Mario Ortiz +4 more
doaj +1 more source
Conformational States of Polymers Adsorbed on Interfaces [PDF]
Polymer Journal, 1991 Adsorbed layer thickness (t) of several dilute polymeric systems were measured by ellipsometry. For physically adsorbed homopolymers, t scales as M0.5 and M0.4 in theta and good solvents, respectively. Conformational change from “mushroom” to “brush” were observed for a terminally attached polyelectrolyte by adjusting electrostatic “excluded volume ...
openaire +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
DEPLOYMENT OF A DEEP LEARNING MODEL TO ASSIST PATHOLOGISTS WITH DONOR KIDNEY BIOPSY EVALUATION
Journal of Pathology Informatics, 2022 Joseph Gaut +5 more
doaj +1 more source