Results 51 to 60 of about 3,381 (218)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
St. Petersburg Polytechnical University Journal: Physics and MathematicsThe study of BP layers and BP/n-Si heterojunctions formed by plasma enhanced chemical deposition on n-Si substrates has been carried out at a temperature of 350 °C using diborane and phosphine.
Baranov Artem +5 more
doaj +1 more source
Hyomen Kagaku, 1999 The energy distribution of interface states in the Si band-gap present at ultra-thin silicon oxide/Si interfaces is obtained from XPS measurements under bias. The substrate Si 2p peak for the MOS structure is shifted by the application of a bias voltage to the Si with respect to the Pt, due to the accumulation of charges in the interface states in ...
openaire +2 more sources
The Möbius State-Level Abstract Functional Interface [PDF]
Performance Evaluation, 2002 A key advantage of the Mobius modeling environment is the ease with which one can incorporate new modeling formalisms, model composition and connection methods, and model solution methods. We present a new state-level abstract functional interface (AFI) for Mobius that allows numerical solution methods to communicate with Mobius state-level models via ...
Salem Derisavi +3 more
openaire +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Applied Sciences, 2018 Information on localized states at the interfaces of solution-processed organic semiconductors and polymer gate insulators is critical to the development of printable organic field-effect transistors (OFETs) with good electrical performance.
Hideyuki Hatta +7 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Frontiers in Human Neuroscience, 2022 Brain-computer interfaces (BCIs) have been successfully used by adults, but little information is available on BCI use by children, especially children with severe multiple impairments who may need technology to facilitate communication.
Jane E. Huggins +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Brain-machine interfaces (BMIs) can improve the control of assistance mobility devices making its use more intuitive and natural. In the case of an exoskeleton, they can also help rehabilitation therapies due to the reinforcement of neuro-plasticity ...
Mario Ortiz +5 more
doaj +1 more source