Results 81 to 90 of about 98,491 (346)

Detecting Mycobacterium tuberculosis Infection in Children Migrating to Australia

Emerging Infectious Diseases, 2022
In 2015, Australia updated premigration screening for tuberculosis (TB) disease in children 2–10 years of age to include testing for infection with Mycobacterium tuberculosis and enable detection of latent TB infection (LTBI).
Ingrid Laemmle-Ruff, Stephen M. Graham, Bridget Williams, Danielle Horyniak, Suman S. Majumdar, Georgia A. Paxton, Lila V. Soares Caplice, Margaret E. Hellard, James M. Trauer   +8 more
doaj   +1 more source

EPIDEMIOLOGY OF TUBERCULOSIS IN INTERNATIONALLY DISPLACED CHILDREN RESETTLING IN HARRIS COUNTY [PDF]

, 2019
Background More than 300,000 refugees arrived in the United States (U.S.) from 2010-2015, and Texas accepts the 2nd highest number of refugees. Texas also accepts large numbers of asylees, parolees, and special immigrant visa holders.
LAMB, GABRIELLA S
core   +1 more source

Quantitative Interferon Gamma Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis: A Prospective Cohort Study.

American Journal of Respiratory and Critical Care Medicine, 2019
RATIONALE Development of diagnostic tools with improved predictive value for tuberculosis (TB) is a global research priority. OBJECTIVES We evaluated whether implementing higher diagnostic thresholds than currently recommended for QuantiFERON Gold-in ...
Rishi K. Gupta, M. Lipman, C. Jackson, A. Sitch, J. Southern, F. Drobniewski, J. Deeks, Chuen-Yan Tsou, C. Griffiths, J. Davidson, C. Campbell, Oliver Stirrup, M. Noursadeghi, H. Kunst, P. Haldar, A. Lalvani, I. Abubakar   +16 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Host factors associated to false negative and indeterminate results in an interferon‐γ release assay in patients with active tuberculosis

Pulmonology, 2020
Introduction Information on host factors that contribute to false negative and indeterminate results in interferon‐γ release assays (IGRA) are critical to improve the usefulness of these tests in the fight against tuberculosis (TB) epidemics.The aim of ...
J.A. Santos, R. Duarte, C. Nunes
doaj   +1 more source

Antigen-Specific IP-10 Release Is a Sensitive Biomarker of Mycobacterium bovis Infection in Cattle. [PDF]

PLoS ONE, 2016
The most widely used ante-mortem diagnostic tests for tuberculosis in cattle are the tuberculin skin test and the interferon-gamma (IFN-γ) release assay, both of which measure cell-mediated immune responses to Mycobacterium bovis infection.
Sven D C Parsons, Kevina McGill, Mairead B Doyle, Wynand J Goosen, Paul D van Helden, Eamonn Gormley   +5 more
doaj   +1 more source

Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]

, 1986
Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA, Gianturco, SH, Gutterman, JU, Kurzrock, R, Quesada, JR, Rohde, MF, Sherwin, SA   +6 more
core  

Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer. [PDF]

, 2017
BackgroundT cells engineered to express chimeric antigen receptors (CARs) have established efficacy in the treatment of B-cell malignancies, but their relevance in solid tumors remains undefined.
A Molinolo, A Stasi Di, A Thor, B Fisher, BA Irving, BL Levine, C Romeo, CC Kloss, CY Wu, D Moritz, DL Porter, DW Lee, F Guadagni, HM Finney, I Blanco, I Stancovski, J Scholler, JD Wolchok, JL Murray, JN Kochenderfer, JW Greiner, KD Griffith, L Naldini, M Hegde, M Kalos, ME Dudley, MH Finer, MH Kershaw, ML Davila, MR Lander, N Gonzales, NP Restifo, P Hwu, RA Morgan, RE Walker, RF Meredith, RP McGuinness, RT Mitsuyasu, S Guedan, SD Patel, SG Deeks, SL Maude, SV Kashmiri   +42 more
core   +1 more source

A tuberculosis contact investigation involving a large number of contacts tested with interferon-gamma release assay at a nursing school: Kanagawa, Japan, 2012

Western Pacific surveillance and response journal : WPSAR, 2018
In May 2012, a teacher of a nursing school with about 300 staff members and students in Japan was diagnosed with sputum smear-positive pulmonary tuberculosis (TB), leading to an investigation involving nearly 300 contacts.
M. Tasaka, T. Shimamura, M. Iwata, T. Toyozawa, M. Ota   +4 more
semanticscholar   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source