Results 31 to 40 of about 1,191,146 (396)
Interferon beta in multiple sclerosis: experience in a British specialist multiple sclerosis centre [PDF]
, 2003 Background: The efficacy of interferon beta (IFN beta) is well established in relapsing-remitting multiple sclerosis (MS). However, the use of this drug in clinical practice is complex, especially because it is only partially effective, its long term ...
Dubois, B.D. +7 more
core +2 more sources
Regulation of hematopoietic stem cell activity by inflammation
Frontiers in Immunology, 2013 Hematopoietic stem cells (HSCs) are quiescent cells with self-renewal capacity and the ability to generate all mature blood cells. HSCs normally reside in specialized niches in the bone marrow that help maintain their quiescence and long-term ...
Laura eSchuettpelz, Daniel eLink
doaj +1 more source
Pseudomonas aeruginosa Modulates the Antiviral Response of Bronchial Epithelial Cells
Frontiers in Immunology, 2020 Cystic fibrosis (CF) patients frequently acquire Pseudomonas aeruginosa infections that have been associated with a bad prognosis and an increased rate of pulmonary exacerbations.
Michael Sörensen +15 more
doaj +1 more source
The Interplay between the Host Microbiome and Pathogenic Viral Infections
mBio, 2021 The microorganisms associated with an organism, the microbiome, have a strong and wide impact in their host biology. In particular, the microbiome modulates both the host defense responses and immunity, thus influencing the fate of infections by ...
Rubén González, Santiago F. Elena
doaj +1 more source
Synthesis of IFN-β by Virus-Infected Chicken Embryo Cells Demonstrated with Specific Antisera and a New Bioassay [PDF]
, 2004 Transcripts of interferon-α(IFN-α) and IFN-β genes are present in virus-infected chicken cells, but because of a lack of appropriate assays and reagents, it was unclear if biologically active IFN-β is secreted.
Harlin, Olof +4 more
core +1 more source
Elevated Levels of Proinflammatory Cytokines in Cerebrospinal Fluid of Multiple Sclerosis Patients
Frontiers in Immunology, 2017 Multiple sclerosis (MS) is an autoimmune neurodegenerative disease characterized by chronic brain inflammation. Leukocyte infiltration of brain tissue causes inflammation, demyelination, and the subsequent formation of sclerotic plaques, which are a ...
Timur Khaibullin +8 more
doaj +1 more source
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core +2 more sources
Frontiers in Microbiology, 2018 H9N2 influenza A viruses (IAV) are considered low pathogenic avian influenza viruses (LPAIV). These viruses are endemic in poultry in many countries in Asia, the Middle East and parts of Africa.
Laura Rodriguez +5 more
doaj +1 more source
Russian Open Medical Journal, 2020 Background ― A number of studies confirmed a crucial role of type 1 interferon in pathophysiology of connective tissue diseases. Interferon regulatory factors (IRF) coordinate an expression of type 1 interferon, while interferon regulatory factor 5 (IRF5)
Mikhail Yu. Krylov +2 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundAltered innate defense mechanisms, including an imbalance between oxidants and antioxidants release, have been implicated in the pathogenesis of chronic rhinosinusitis (CRS).
Sang Hag Lee +6 more
doaj +1 more source