Results 51 to 60 of about 675,714 (307)

Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon [PDF]

, 2009
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs).
Shin, Young Chul, Johannsen, Eric, Haas, Juergen, Hyun Joo, Chul, Fossum, Even, Hutt-Fletcher, Lindsay M., Wu, L., Inn, Kyung-Soo, Jung, Jae U.   +8 more
core   +1 more source

Interferon-γ production in QuantiFERON-TB Gold Plus tubes in 10 contacts with reversion.

, 2023
Interferon-γ production in QuantiFERON-TB Gold Plus tubes in 10 contacts with reversion.
Paloma Gijón-Vidaurreta (16907743), Carmen Martos (3583643), M. Jesús Ruiz-Serrano (16907764), Anton Penas-Truque (16907761), Sandra Pérez-Recio (16907731), Fernando Alcaide (4401190), María Jesús Santos (16907752), Luis Anibarro (9118514), Miguel Santin (330610), Erika I. Garcia-de-Cara (16907767), Ramón Rabuñal-Rey (16907737), Matilde Trigo (830322), Sara Rodríguez (88448), Esther Moga (16907758), Virginia Pomar (237258), Mercedes García-Gasalla (16907746), Maria D. Grijota-Camino (16907734), Ángel Domínguez-Castellano (16907749), Alba Cebollero (16907755), Josefina Sabria (16907740)   +19 more
core   +1 more source

Disparate viral pandemics from COVID19 to monkeypox and beyond: a simple, effective and universal therapeutic approach hiding in plain sight

Frontiers in Immunology, 2023
The field of antiviral therapeutics is fixated on COVID19 and rightly so as the fatalities at the height of the pandemic in the United States were almost 1,000,000 in a twelve month period spanning parts of 2020/2021.
Howard M. Johnson, Chulbul M. Ahmed
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interferon-gamma responses by CD8+ PBMC fractions to the 8-10mer CSP peptides.

, 2020
Interferon-gamma responses by CD8+ PBMC fractions to the 8-10mer CSP peptides.
Michael Hollingdale (3546365), Eileen Villasante (628418), Eric Kyei-Baafour (3358949), Martha Sedegah (201887), Felix E. Aggor (8431422), Kwadwo A. Kusi (8431419), Daniel Amoako-Sakyi (502592), Dorcas Obiri-Yeboah (844157), Bjoern Peters (19131), Linda E. Amoah (2491204), Yvonne Nartey (8431425), Harini Ganeshan (83061), Maria Belmonte (201939), Daniel Dodoo (40242), Yohan Kim (49009), Dorothy Anum (3564485), John Tetteh (3564482)   +16 more
core   +1 more source

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]

, 2010
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M., Suhrbier, A., Corinne Geertsema, Esther Schnettler, Fros, J., Just M. Vlak, Maarten Ligtenberg, Geertsema, C., Suhrbier, Andreas, Wen Jun Liu, Natalie A. Prow, Vlak, J.M., Dana L. Vanlandingham, Ligtenberg, Maarten, Khromykh, Alexander A., Jelke J. Fros, Vanlandingham, D.L., Vlak, Just M., Schnettler, E., Fros, J.J., Gorben P. Pijlman, Pijlman, G.P., Liu, W.J., Khromykh, A.A., Prow, A., Fros, Jelke J., Vanlandingham, Dana L., Liu, Wen Jun, Geertsema, Corinne, Prow, Natalie A., Alexander A. Khromykh, Schnettler, Esther, Pijlman, Gorben P., Andreas Suhrbier, Prow, N.A.   +34 more
core   +1 more source

“Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective

Cells, 2020
Cells are constantly challenged by pathogens (bacteria, virus, and fungi), and protein aggregates or chemicals, which can provoke membrane damage at the plasma membrane or within the endo-lysosomal compartments.
Coralie F. Daussy, Harald Wodrich
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]

, 2012
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga, Raffaele Malinverni, Gerlach, Tilman J., Gerlach, Tilman J, Tilman J Gerlach, Swiss Hepatitis C Cohort Study Group,, Berg, T., Kutalik, Z., Stephanie Bibert, Christian M Lange, Geier, Andreas, Dufour, Jean-François Jacques, Thomas Berg, Malinverni, Raffaele, Regenass, S., Burgisser, Philippe, Regenass, Stephan, Badenhoop, Klaus, Bojunga, Jörg, Lange, Christian M, Dufour, J. F., Stephan Regenass, Gerlach, Tilman Joern, Swiss Hepatitis C Cohort Study Group, Bochud, P. Y., Dufour, Jean-Francois, Bojunga, J., Andreas Geier, Stefan Zeuzem, Negro, F., Cerny, A., Zoltan Kutalik, Lange, Christian, Pierre-Yves Bochud, Sarrazin, C., Tobias Müller, Sarrazin, Christoph, Lange, C. M., Cerny, Andreas, Kutalik, Zoltán, Bibert, S., Malinverni, R., Moradpour, Darius, Christoph Sarrazin, Burgisser, P., Gerlach, T. J., Moradpour, D., Bibert, Stephanie, Klaus Badenhoop, Zeuzem, S., Negro, Francesco, Müller, Tobias, Badenhoop, K., Andreas Cerny, Bochud, Pierre-Yves, Geier, A., Heim, M. H., Muller, T., Francesco Negro, Berg, Thomas, Markus H Heim, Heim, Markus H., Darius Moradpour, Jean-Francois Dufour, Philippe Burgisser, Heim, Markus H, Zeuzem, Stefan, Gerlach, T.J., Heim MH, Geier A, Müller Tobias, Moradpour D, Burgisser Philippe, Malinverni Raffaele, Badenhoop K, Bochud Pierre-Yves, Regenass Stephan, Dufour Jean-Francois, Regenass S, Dufour JF, Negro Francesco, Cerny A, Zeuzem Stefan, Bochud, P.Y., Dufour, J.F., Heim Markus H., Berg Thomas, Geier Andreas, Berg T, Sarrazin Christoph, Burgisser P, Malinverni R, Badenhoop Klaus, Bojunga Jörg, Zeuzem S, Bochud PY, Cerny Andreas, Sarrazin C, Bibert Stephanie, Moradpour Darius, Bibert S, Lange CM, Kutalik Z, Kutalik Zoltan, Lange Christian M., Lange, C.M., Gerlach Tilman J., Heim, M.H., Gerlach TJ, Negro F, Müller T, Bojunga J   +111 more
core   +2 more sources

Molecular Mechanisms of Immune Escape for Foot-and-Mouth Disease Virus

Pathogens, 2020
Foot-and-mouth disease virus (FMDV) causes a highly contagious vesicular disease in cloven-hoofed livestock that results in severe consequences for international trade, posing a great economic threat to agriculture.
Bo Yang, Xiaohui Zhang, Dajun Zhang, Jing Hou, GuoWei Xu, Chaochao Sheng, Sk Mohiuddin Choudhury, Zixiang Zhu, Dan Li, Keshan Zhang, Haixue Zheng, Xiangtao Liu   +11 more
doaj   +1 more source