Results 31 to 40 of about 656,599 (299)

Dynamics of Transforming Growth Factor (TGF)-β Superfamily Cytokine Induction During HIV-1 Infection Are Distinct From Other Innate Cytokines

Frontiers in Immunology, 2020
Human immunodeficiency virus type 1 (HIV-1) infection triggers rapid induction of multiple innate cytokines including type I interferons, which play important roles in viral control and disease pathogenesis.
Matthew Dickinson, Matthew Dickinson, Anna E. Kliszczak, Eleni Giannoulatou, Eleni Giannoulatou, Dimitra Peppa, Dimitra Peppa, Pierre Pellegrino, Ian Williams, Hal Drakesmith, Persephone Borrow   +10 more
doaj   +1 more source

Virus Infections and Host Metabolism—Can We Manage the Interactions?

Frontiers in Immunology, 2021
When viruses infect cells, they almost invariably cause metabolic changes in the infected cell as well as in several host cell types that react to the infection.
Deepak Sumbria, Engin Berber, Engin Berber, Manikannan Mathayan, Barry T. Rouse   +4 more
doaj   +1 more source

Bunyaviruses and the type I interferon system [PDF]

, 2009
The family Bunyaviridae contains more than 350 viruses that are distributed throughout the world. Most members of the family are transmitted by arthopods, and several cause disease in man, domesticated animals and crop plants. Despite being recognized as
Richard M. Elliott, Weber, F., Richard Elliott, Richard M. Elliott, Elliott, Richard Michael, Friedemann Weber, Weber, F, Elliott, R.M.   +7 more
core   +1 more source

Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection

Cell Reports Medicine, 2020
Summary: Lung transplantation can be lifesaving in end-stage cystic fibrosis (CF), but long-term survival is limited by chronic lung allograft dysfunction (CLAD).
Daniel T. Dugger, Monica Fung, Lorna Zlock, Saharai Caldera, Louis Sharp, Steven R. Hays, Jonathan P. Singer, Lorriana E. Leard, Jefferey A. Golden, Rupal J. Shah, Jasleen Kukreja, Erin Gordon, Walter Finkbeiner, Mary Ellen Kleinhenz, Chaz Langelier, John R. Greenland   +15 more
doaj   +1 more source

Influenza virus activation of the interferon system [PDF]

, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin, Killip, Marian J., Randall, RE, Fodor, E., Killip, MJ, Randall, Richard E., Fodor, E, Killip, M.J., Randall, R.E.   +8 more
core   +1 more source

Interferon signalling in the liver : implications for the natural course and therapy of hepatitis C [PDF]

, 2012
Hepatitis C virus is a global health concern, estimated to infect 2-3% of the world's population. Inter-individual differences in the course of infection and response to therapy, highlighted by recent genomewide association studies, point to the crucial ...
Makowska, Zuzanna
core   +1 more source

Oral Supplementation of Houttuynia cordata Extract Reduces Viremia in PRRSV-1 Modified-Live Virus-Vaccinated Pigs in Response to the HP-PRRSV-2 Challenge

Frontiers in Immunology, 2022
This study evaluated the in vitro antiviral activities and the ex vivo immunomodulatory effects of Houttuynia cordata Thunb. (HC) ethanolic extracts in response to porcine reproductive and respiratory syndrome virus (PRRSV).
Wilawan Ruansit, Wasin Charerntantanakul
doaj   +1 more source

An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response [PDF]

, 2014
Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, IFN-dependent upregulation of IFN-stimulated genes (ISGs) and the activity of various ...
Fernández, Yolanda, Oliveros, JC, Randall, Richard E, Asensio, Víctor J, Killip, Marian J., Randall, RE, Oliveros, Juan Carlos, Killip, Marian J, Asensio, Víctor J., Bengoechea, Jose Antonio, Oliveros, Juan C., Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Bengoechea, JA, Bengoechea, José A; id_orcid, Ortín, Juan, Killip, MJ, Ortín, J, Asensio, Víctor José, Randall, Richard E., Bengoechea, José A., Asensio, VJ, Oliveros, Juan C, Fernández, Y   +23 more
core   +1 more source

Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model

Frontiers in Immunology, 2018
DDX41 is an important sensor for host recognition of DNA viruses and initiation of nuclear factor-κB (NF-κB) and IFN signaling pathways in mammals. However, its occurrence and functions in other vertebrates remain poorly defined.
Jun-xia Ma, Jiang-yuan Li, Dong-dong Fan, Wei Feng, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao, Jian-zhong Shao   +7 more
doaj   +1 more source

The novel immunobiotic Clostridium butyricum S-45-5 displays broad-spectrum antiviral activity in vitro and in vivo by inducing immune modulation

Frontiers in Immunology, 2023
Clostridium butyricum is known as a probiotic butyric acid bacterium that can improve the intestinal environment. In this study, we isolated a new strain of C.
Kiramage Chathuranga, Yeseul Shin, Md Bashir Uddin, Md Bashir Uddin, Md Bashir Uddin, Jayoung Paek, W. A. Gayan Chathuranga, Yebin Seong, Lu Bai, Hongik Kim, Jeong Hwan Shin, Young-Hyo Chang, Jong-Soo Lee   +12 more
doaj   +1 more source