Results 11 to 20 of about 327,168 (302)

The value of interferon therapy for COVID-19 in children

Детские инфекции (Москва), 2021
The article presents a literature review, which provides data on the role of interferons in the immunopathogenesis of COVID-19 and the clinical efficacy of drugs based on recombinant interferon-alpha 2b in the treatment of children with new coronavirus ...
L. N. Mazankova, S. G. Gorbunov, E. R. Samitova   +2 more
doaj   +1 more source

Antiviral Activity of Interferon Alpha-2b and Taurine Combination Against SARS-CoV-2 in vitro

Антибиотики и Химиотерапия, 2022
Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in the Russian Federation, and its antiviral activity has not been studied before.
N. P. Kartashova, A. V. Ivanina, E. A. Glubokova, I. N. Falynskova, A. A. Poromov, I. A. Leneva   +5 more
doaj   +1 more source

Interferon impedes an early step of hepatitis delta virus infection. [PDF]

PLoS ONE, 2011
Hepatitis delta virus (HDV) infects hepatocytes, the major cell type of the liver. Infection of the liver may be either transient or chronic. The prognosis for patients with chronic HDV infection is poor, with a high risk of cirrhosis and hepatocellular ...
Ziying Han, Shoko Nogusa, Emmanuelle Nicolas, Siddharth Balachandran, John Taylor   +4 more
doaj   +1 more source

Enhanced anti-HCV activity of interferon alpha 17 subtype

Virology Journal, 2009
Background Pegylated interferon alpha 2 (a or b) plus ribavirin is the most effective treatment of chronic hepatitis C but a large proportion of patients do not respond to therapy. So, it is interesting to improve the treatment efficacy. Interferon alpha
Dubuisson Jean, Wychowski Czeslaw, Fournier Carole, Descamps Veronique, François Catherine, Dubois Aurelie, Castelain Sandrine, Duverlie Gilles   +7 more
doaj   +1 more source

Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]

, 2003
Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L, Lau, Helen Y, Monteleon, Christine L, Moore, Thomas A, Standiford, Theodore J   +4 more
core   +1 more source

Expression of interferon-alpha subtypes in peripheral mononuclear cells from patients with chronic hepatitis C: a role for interferon-alpha5 [PDF]

, 2001
Interferon (IFN)-alpha is a family of antiviral proteins encoded by different genes. The biological significance of the existence of various IFN-alpha subtypes is not clear.
Alberdi, A. (A.), Boya, P. (Patricia), Castelruiz, Y. (Yurdana), Civeira, M.P. (María Pilar), Larrea, E. (Esther), Prieto, J. (Jesús)   +5 more
core   +1 more source

Prediction of sustained remission of chronic hepatitis C after a 12-month course of alfa interferon [PDF]

, 1994
alpha-Interferon therapy normalizes aminotransferase levels in approximately 50% of the patients with chronic hepatitis C, but post-therapy relapses are common and predictive factors of sustained response remain largely unknown.
Alava, E. (Enrique) de, Camps, J. (J.), Castilla, A. (Alberto), Civeira, M.P. (María Pilar), Garcia-Granero, M. (Marta), Larrea, E. (Esther), Prieto, J. (Jesús), Riezu-Boj, J.I. (José Ignacio)   +7 more
core   +1 more source

Vaginal biocenosis in pregnant women with recurrent bacterial vaginosis after treatment with recombinant human interferon alpha-2b

Акушерство, гинекология и репродукция, 2019
Introduction. Preventing recurrent bacterial vaginosis (BV) during pregnancy is an important issue in current obstetrics.Aim: to assess the effect of recombinant human interferon alpha-2b on the incidence of recurrent BV during pregnancy and on the ...
A. V. Podgornaya, A. Sh. Makhmutkhodzhaev   +1 more
doaj   +1 more source

Clinical-evolutional particularities of the cryoglobulinemic vasculitis in the case of a patient diagnosed with hepatitis C virus in the predialitic phase [PDF]

, 2018
Hepatitis C virus (HCV) represents a fundamental issue for public health, with long term evolution and the gradual appearance of several complications and associated pathologies.
Boldeanu, Lidia, Boldeanu, Mihail V., Caragea, Daniel C., Ciurea, Marius E., Ciurea, Tudorel, Forțofoiu, Maria, Forțofoiu, Mircea C., Popescu-Drigă, Mircea, Pădureanu, Vlad, Rogoveanu, Ion, Streba, Costin, Săndulescu, Larisa, Vere, Cristin C.   +12 more
core   +3 more sources

Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]

, 2006
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel, Baudoux, BERNARD CHARLEY, Brim, Charley, Charley, Charley, Chen, Chinsangaram, Corthier, Fitzgerald-Bocarsly, Guzylack-Piriou, Heinen, KRISTIEN VAN REETH, La Bonnardière, Laude, Laude, Le Bon, Lim, Liu, Palese, Peiris, Pestka, Riffault, Riffault, Riffault, Rothenfusser, SABINE RIFFAULT, Saif, Siegal, Summerfield, Tu, Tudor, Van Reeth, Van Reeth, van Reeth   +35 more
core   +2 more sources