Results 21 to 30 of about 128,935 (252)

Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-γ, interleukin-4, tumor necrosis factor-α, or muramyl dipeptide

International Journal of Immunopathology and Pharmacology, 2017
Keratinocytes are routinely subjected to both internal and external stimulation. This study investigates the effects of interferon gamma, interleukin-4, tumor necrosis factor alpha, and the synthetic immunomodulator muramyl dipeptide on the human ...
Emale El Darzi, Samer Bazzi, Sarah Daoud, Karim S Echtay, Georges M Bahr   +4 more
doaj   +1 more source

Interferon-gamma alters the phagocytic activity of the mouse trophoblast

Reproductive Biology and Endocrinology, 2005
Interferon-gamma (IFN-gamma) mediates diverse functions in bone marrow-derived phagocytes, including phagocytosis and microbe destruction. This cytokine has also been detected at implantation sites under both physiological and pathological conditions in ...
Abrahamsohn Ises, Leanza Eduardo C, Gagioti Sonia M, Hoshida Mara S, Albieri Andréa, Croy Anne, Ashkar Ali A, Bevilacqua Estela   +7 more
doaj   +1 more source

THE IMMUNOCOMPETENT CELLS RECEPTORS RESEARCH UNDER EXPERIMENTAL INFLUENZA INFECTION IN VITRO

Инфекция и иммунитет, 2015
Introduction. It is known that interferon is a cytokine and is a substantial part of the immune system necessary for antigenic challenge immune response full expression. Also it is considered that every antigen is an interferon inducer.
A. N. Lisakov, F. G. Nagieva, E. P. Barkova, L. A. Gaiderova, A. Y. Fedotov, V. G. Nikulina, M. V. Gavrilova   +6 more
doaj   +1 more source

Acute Plasmodium Infection Promotes Interferon-Gamma-Dependent Resistance to Ebola Virus Infection

Cell Reports, 2020
Summary: During the 2013–2016 Ebola virus (EBOV) epidemic, a significant number of patients admitted to Ebola treatment units were co-infected with Plasmodium falciparum, a predominant agent of malaria.
Kai J. Rogers, Olena Shtanko, Rahul Vijay, Laura N. Mallinger, Chester J. Joyner, Mary R. Galinski, Noah S. Butler, Wendy Maury   +7 more
doaj   +1 more source

Association between IFNGR1 gene polymorphisms and tuberculosis susceptibility: A meta-analysis

Frontiers in Public Health, 2022
The association of IFN-γ receptor 1 (IFNGR1) gene polymorphisms with tuberculosis (TB) susceptibility has not been systematically studied. We therefore conducted a meta-analysis to assess their association.
Liwei Cheng, Fan Zhang, Ying Wang, Jing Chen, Xiaoping Yuan   +4 more
doaj   +1 more source

Interferon gamma‐dependent transactivation of epidermal growth factor receptor [PDF]

FEBS Letters, 2007
The present report provides evidence that, in A431 cells, interferon γ (IFNγ) induces the rapid (within 5 min), and reversible, tyrosine phosphorylation of the epidermal growth factor receptor (EGFR). IFNγ‐induced EGFR transactivation requires EGFR kinase activity, as well as activity of the Src‐family tyrosine kinases and JAK2. Here, we show that IFNγ‐
Burova, Elena, Vassilenko, Konstantin, Dorosh, Victoria, Gonchar, Ilya, Nikolsky, Nikolai   +4 more
openaire   +2 more sources

Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages

Cell Reports, 2020
Summary: Activated macrophages must carefully calibrate their inflammatory responses to balance efficient pathogen control with inflammation-mediated tissue damage, but the molecular underpinnings of this “balancing act” remain unclear. Using genetically
Zahidul Alam, Samir Devalaraja, Minghong Li, Tsun Ki Jerrick To, Ian W. Folkert, Erick Mitchell-Velasquez, Mai T. Dang, Patricia Young, Christopher J. Wilbur, Michael A. Silverman, Xinyuan Li, Youhai H. Chen, Paul T. Hernandez, Aritra Bhattacharyya, Mallar Bhattacharya, Matthew H. Levine, Malay Haldar   +16 more
doaj   +1 more source

Receptors for human gamma interferon: binding and crosslinking of 125I-labeled recombinant human gamma interferon to receptors on WISH cells. [PDF]

Proceedings of the National Academy of Sciences, 1984
Purified recombinant human gamma interferon (HuIFN-gamma), labeled with 125I (125I-HuIFN-gamma), was used to study receptors for HuIFN-gamma on human WISH cells. 125I-HuIFN-gamma was bound to WISH cells, and this binding was displaced by unlabeled HuIFN-gamma but not by unlabeled recombinant HuIFN-alpha 2 or [Ser17]HuIFN-beta (HuIFN-beta with serine ...
F H, Sarkar, S L, Gupta
openaire   +2 more sources

The non-palindromic adaptor-PCR method for the identification of the T-cell receptor genes of an interferon-gamma-secreting T-cell hybridomaspecific for trans-sialidase, an immunodominant Trypanosoma cruzi antigen

Brazilian Journal of Medical and Biological Research, 2006
Cloning of the T-cell receptor genes is a critical step when generating T-cell receptor transgenic mice. Because T-cell receptor molecules are clonotypical, isolation of their genes requires reverse transcriptase-assisted PCR using primers specific for ...
M.I. Hiyane, S.B. Boscardin, M.M. Rodrigues   +2 more
doaj   +1 more source

Transcriptome Sequencing Reveals the Antiviral Innate Immunity by IFN-γ in Chinese Sturgeon Macrophages

Frontiers in Immunology, 2022
To further study the biological function of interferon-gamma (IFN-γ) in the Chinese sturgeon (Acipenser sinensis), we conducted a transcriptome analysis of primary macrophages induced by IFN-γ using Illumina sequencing technology.
Guangyi Ding, Chuwen Zheng, Bei Wang, Lifeng Zhang, Dan Deng, Qian Li, Huizhi Guo, Shuhuan Zhang, Qiaoqing Xu, Qiaoqing Xu   +9 more
doaj   +1 more source