Results 201 to 210 of about 20,854 (255)

Combine immune checkpoint indoleamine 2,3-dioxygenase 1 knockdown with ferroptosis inducer Erastin/RSL3 accelerates colorectal cancer cell ferroptosis. [PDF]

Cytojournal
Li F, Xu T, Ling Y, Xu J, Zhang X, Sun S.   +5 more
europepmc   +1 more source

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

Advanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, Kun Qian, Jing Zuo   +11 more
wiley   +1 more source

Harnessing Cuproptosis for Antitumor Immunity: A Review of Current Evidence and Therapeutic Strategies. [PDF]

Mol Carcinog
Lu I, Zhang J, Chen X, Wang XJ.
europepmc   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Unlocking the Secrets of Regulated Cell Death in Large B-Cell Lymphoma Beyond Apoptosis: Signaling Pathways and Therapeutic Options. [PDF]

Int J Mol Sci
Tkachenko A, Havranek O.
europepmc   +1 more source

Ferroptosis and Radiotherapy in Lung Cancer. [PDF]

Cells
Patel PC, Galvan EM.
europepmc   +1 more source

Ferroptosis in Anaplastic Thyroid Cancer: Molecular Mechanisms, Preclinical Evidence, and Therapeutic Prospects. [PDF]

Cells
Lee J, Roh JL.
europepmc   +1 more source

The Molecular Signature of Early-Onset Colorectal Cancer Liver Metastases: Distinct Biology and Clinical Challenges. [PDF]

Int J Mol Sci
Tsokkou S, Konstantinidis I, Chatzikomnitsa P, Papakonstantinou M, Gkaitatzi AD, Toutziari E, Alexandrou D, Giakoustidis D, Papadopoulos VN, Giakoustidis A.   +9 more
europepmc   +1 more source

CTRP6 as a negative regulator of anti-inflammatory M2 macrophage polarization. [PDF]

Immunometabolism (Cobham)
Senthil Kumar J, Kempton E, Mehboob MZ, Lin D, Lei X.   +4 more
europepmc   +1 more source

Ferroptosis and metabolic reprogramming in the immunosuppressive microenvironment of glioblastoma: emerging mechanisms and novel strategies. [PDF]

Front Immunol
Han L, Wang Z, Jiang Y, Zhou H, Zhou H.
europepmc   +1 more source