Results 241 to 250 of about 50,714 (355)

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Self-aggregating Lactiplantibacillus plantarum enhances type-I interferon responses via the cytosolic sensors NOD2 and cGAS. [PDF]

Gut Microbes
Solis S, Maldonado EM, Mukhopadhyay S, Jan G, Landete JM, Maluquer de Motes C, Gutierrez-Merino J.   +6 more
europepmc   +1 more source

The Role of Interferon-γ Inducible Protein-10 in a Mouse Model of Acute Liver Injury Post Induced Pluripotent Stem Cells Transplantation

, 2012
Che-Chang Chan, Ling‐Yi Cheng, Jean Lu, Yi‐Hsiang Huang, Shih-Hwa Chiou, Ping‐Hsing Tsai, Teh‐Ia Huo, Han-Chieh Lin, Fa‐Yauh Lee   +8 more
openalex   +2 more sources

Interleukin-12 (IL-12) and IL-18 synergistically induce the fungicidal activity of murine peritoneal exudate cells against Cryptococcus neoformans through production of gamma interferon by natural killer cells [PDF]

, 1997
T Zhang, Kazuyoshi Kawakami, Mahboob Qureshi, Haruki Okamura, M Kurimoto, Atsushi Saitô   +5 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Metabolic cell deaths in head and neck cancer: mechanisms, therapeutic potential, and challenges. [PDF]

Ann Med
Wang T, Li X, Huang X, Wang Z, Zhang Y, Lei J, Qian X, Lu C, Liu Z.   +8 more
europepmc   +1 more source

Table 12_The DEAD-box RNA helicase 27 negatively regulates the replication of porcine reproductive and respiratory syndrome virus by mediating GP2a autophagy degradation and inducing interferon-β production.xlsx

Binghua Chen (236328), Yunyan Luo (12185358), Yongjie Chen (269938), Jingxing Wang (3079734), Jiecong Yan (21528902), Zhan He (3112443), Fangfang Li (1972918), Chunhe Guo (5549639)   +7 more
openalex   +1 more source

Interferon-γ Induces Chronic Active Myocarditis and Cardiomyopathy in Transgenic Mice [PDF]

, 2007
Kurt Reifenberg, Hans-Anton Lehr, Michael Torzewski, Gisela Steige, Elena Wiese, Ines Küpper, Christoph Becker, Sibylle Ott, Petra Nusser, Ken–ichi Yamamura, Gerd Rechtsteiner, Tobias Warger, Andrea Pautz, Hartmut Kleinert, Albrecht Schmidt, Burkert Pieske, Philip Wenzel, Thomas Münzel, Jürgen Löhler   +18 more
openalex   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Immune Modulation in Cancer: The Role of Tumor-Treating Fields (TTFields). [PDF]

Curr Protoc
Liu M, Hage ME, Zhao J, Linnebacher M.
europepmc   +1 more source