Results 121 to 130 of about 332,508 (311)

Correction: Clinical efficacy and safety of interferon (Type I and Type III) therapy in patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials. [PDF]

PLoS One, 2023
Ryoo S, Koh DH, Yu SY, Choi M, Huh K, Yeom JS, Heo JY.   +6 more
europepmc   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Defective interfering particles of parainfluenza virus subtype 5 and interferon induction

, 2015
The innate immune response is the first line of defence against virus infection. Cells contain a diverse array of pathogen recognition receptors (PRRs) that are able to recognise multiple pathogen associated molecular patterns (PAMPS) that present ...
Short, John A. L.
core  

Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen

Cell Reports, 2017
How type I and II interferons prevent periodic reemergence of latent pathogens in tissues of diverse cell types remains unknown. Using homogeneous neuron cultures latently infected with herpes simplex virus 1, we show that extrinsic type I or II ...
Jessica A. Linderman, Mariko Kobayashi, Vinayak Rayannavar, John J. Fak, Robert B. Darnell, Moses V. Chao, Angus C. Wilson, Ian Mohr   +7 more
doaj   +1 more source

Evaluation of the interaction between tumor growth factor-β and interferon type I pathways in patients with COVID-19: focusing on ages 1 to 90 years. [PDF]

BMC Infect Dis, 2023
Abbasifard M, Fakhrabadi AH, Bahremand F, Khorramdelazad H.   +3 more
europepmc   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response

, 2011
The host determinants that contribute to attenuation of the naturally occurring nonpathogenic strain of West Nile virus (WNV), the Kunjin strain (WNVKUN), remain unknown.
Lazear, Helen, Diamond, Michael S., Engle, Michael, Wen Jun Liu, Khromykh, Alexander, Lazear, Helen M., Liu, Wen Jun, Khromykh, Alexander A., Helen M. Lazear, Daffis, Stephane, Michael Engle, Alexander A. Khromykh, Stephane Daffis, Michael S. Diamond, Audsley, Michelle, Diamond, Michael, Michelle Audsley, Liu, Wen   +17 more
core   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Context-dependent impact of type I interferon signaling in cancer

Molecular Cancer
Type I interferon (IFN) has long been known as a critical component of the molecular machinery that first responds to viral infection in multicellular eukaryotes.
Ainhoa Ruiz-Iglesias, Emma Guilbaud, Lorenzo Galluzzi, Santos Mañes   +3 more
doaj   +1 more source

Astrocyte Control of Zika Infection Is Independent of Interferon Type I and Type III Expression. [PDF]

Biology (Basel), 2022
Das M, Smith ML, Furihata T, Sarker S, O'Shea R, Helbig KJ.   +5 more
europepmc   +1 more source