Results 31 to 40 of about 223,138 (357)
Immuno, 2022 The pathogenesis of COVID-19 is complicated by immune dysfunction. The impact of immune-based therapy in COVID-19 patients has been well documented, with some notable studies on the use of anti-cytokine medicines.
Deepshikha Yadav +12 more
doaj +1 more source
Immunity, Inflammation and Disease, 2018 Background Mast cells are resident immune effector cells, often studied in the context of allergic disease. Found in substantial numbers at sites of potential infection they are increased at sites of angiogenesis and can be pivotal for the sensing and ...
Sharon A. Oldford +6 more
doaj +1 more source
Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System
Viruses, 2021 Viral infections remain a global public health concern and cause a severe societal and economic burden. At the organismal level, the innate immune system is essential for the detection of viruses and constitutes the first line of defense.
Hina Singh, Jeffrey Koury, Marcus Kaul
doaj +1 more source
Hepatitis C Virus Infection: Host–Virus Interaction and Mechanisms of Viral Persistence
Cells, 2019 Hepatitis C (HCV) is a major cause of liver disease, in which a third of individuals with chronic HCV infections may develop liver cirrhosis. In a chronic HCV infection, host immune factors along with the actions of HCV proteins that promote viral ...
DeGaulle I. Chigbu +4 more
doaj +1 more source
African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update
Viruses, 2023 African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without control, threatening pig production due to the absence of licensed ...
Giulia Franzoni +2 more
doaj +1 more source
Synthesis of IFN-β by Virus-Infected Chicken Embryo Cells Demonstrated with Specific Antisera and a New Bioassay [PDF]
, 2004 Transcripts of interferon-α(IFN-α) and IFN-β genes are present in virus-infected chicken cells, but because of a lack of appropriate assays and reagents, it was unclear if biologically active IFN-β is secreted.
Harlin, Olof +4 more
core +1 more source
Efficacy of oseltamivir treatment in influenza virus-infected obese mice
mBio, 2023 Obesity has been epidemiologically and empirically linked with more severe diseases upon influenza infection. To ameliorate severe disease, treatment with antivirals, such as the neuraminidase inhibitor oseltamivir, is suggested to begin within days of ...
Rebekah Honce +10 more
doaj +1 more source
Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]
, 2018 Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena +5 more
core +2 more sources
Treatment of hepatitis C virus infection: From therapy with interferon to direct-acting antivirals
Iatreia, 2023 Hepatitis C virus (HCV) infection is a global public health concern. An estimated of 58 million people with chronic HCV infection are at risk of developing cirrhosis or hepatocellular carcinoma.
Laura Lopera +4 more
doaj +1 more source
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity [PDF]
, 2013 Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Benfield, C T O +6 more
core +1 more source