Results 21 to 30 of about 136,515 (265)

Interim and end-treatment 18F-Fluorocholine PET/CT and bone scan in prostate cancer patients treated with Radium 223 dichloride

Scientific Reports, 2021
To assess the predictive and prognostic aim of interim and end-treatment 18F-fluorocholine PET/CT (FCH-PET/CT) and 99mTc-methilen diphosphonate bone scintigraphy (BS) in patients with castration-resistant prostate cancer and bone metastases (CRPC-BM ...
Ana María García Vicente, Mariano Amo-Salas, Javier Cassinello Espinosa, Roberto Gómez Díaz, Ángel Soriano Castrejón   +4 more
doaj   +1 more source

Azithromycin: An Interim Analysis

Journal of International Medical Research, 1991
Azithromycin, a novel azalide antibiotic structurally related to erythromycin, has been shown by in vitro studies to have similar activity to erythromycin against Gram-positive pathogens but additionally to have increased activity against some Gram-negative bacteria, notably Haemophilus influenzae.
openaire   +2 more sources

Approaches to interim analysis of cancer randomised clinical trials with time to event endpoints: A survey from the Italian National Monitoring Centre for Clinical Trials

Trials, 2008
Background Although interim analysis approaches in clinical trials are widely known, information on current practice of planned monitoring is still scarce.
De Rosa Marisa, Torri Valter, Albertazzi Elena, Rotmensz Nicole, Floriani Irene, Tomino Carlo, de Braud Fillipo   +6 more
doaj   +1 more source

Rosiglitazone Evaluated for Cardiovascular Outcomes — An Interim Analysis [PDF]

New England Journal of Medicine, 2007
A recent meta-analysis raised concern regarding an increased risk of myocardial infarction and death from cardiovascular causes associated with rosiglitazone treatment of type 2 diabetes.We conducted an unplanned interim analysis of a randomized, multicenter, open-label, noninferiority trial involving 4447 patients with type 2 diabetes who had ...
Home, Philip D, Pocock, Stuart J, Beck-Nielsen, Henning, Gomis, Ramón, Hanefeld, Markolf, Jones, Nigel P, Komajda, Michel, McMurray, John J V, Study Group, RECORD   +8 more
openaire   +3 more sources

Effect of high-flow nasal therapy on patient-centred outcomes in patients at high risk of postoperative pulmonary complications after cardiac surgery: a statistical analysis plan for NOTACS, a multicentre adaptive randomised controlled trial

Trials, 2022
Background The NOTACS trial will assess the efficacy, safety and cost-effectiveness of high-flow nasal therapy (HFNT) compared to standard oxygen therapy (SOT) on the outcomes of patients after cardiac surgery.
Sarah N. Dawson, Yi-Da Chiu, Andrew A. Klein, Melissa Earwaker, Sofia S. Villar   +4 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

HOAPS and ERA-Interim precipitation over the sea: validation against shipboard in situ measurements [PDF]

Atmospheric Measurement Techniques, 2016
The satellite-derived HOAPS (Hamburg Ocean Atmosphere Parameters and Fluxes from Satellite Data) and ECMWF (European Centre for Medium-Range Weather Forecasts) ERA-Interim reanalysis data sets have been validated against in situ precipitation ...
K. Bumke, G. König-Langlo, J. Kinzel, M. Schröder   +3 more
doaj   +1 more source

Guidance on interim analysis methods in clinical trials

Journal of Clinical and Translational Science, 2023
Interim analyses in clinical trials can take on a multitude of forms. They are often used to guide Data and Safety Monitoring Board (DSMB) recommendations to study teams regarding recruitment targets for large, later-phase clinical trials.
Jody D. Ciolino, Alexander M. Kaizer, Lauren Balmert Bonner   +2 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source