Results 41 to 50 of about 277,845 (282)

Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]

, 2015
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo, Stergiopulos, Nikolaos, Trachet, Bram   +2 more
core   +2 more sources

Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]

, 2017
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario, Braghetta, Paola, Bressan, Giorgio M., Carnevale, Daniela, Carnevale, Lorenzo, Carnevale, Raimondo, Casaburo, Manuel, Cifelli, Giuseppe, DA ROS, Francesco, Fardella, Stefania, Iacobucci, Roberta, Lembo, Giuseppe, Perrotta, Marialuisa, Vinciguerra, Iolanda   +13 more
core   +1 more source

Acute Phase Protein Response and Polymorphonuclear Leukocyte Cathepsin G Release After Slow Interleukin-1 Stimulation in the Rat

Mediators of Inflammation, 1994
In this work we have studied the acute phase protein response and degranulation of polymorphonuclear leukocytes in vivo in the rat after a slow interleukin-1β stimulation.
Peter Björk, Thorarinn Gudmundsson, Kjell Ohlsson   +2 more
doaj   +1 more source

MOESM3 of Protective effects of ten oligostilbenes from Paeonia suffruticosa seeds on interleukin-1β-induced rabbit osteoarthritis chondrocytes

, 2019
Additional file 3. Flowchart of the extraction and isolation of oligostilbenes from Paeonia suffruticosa seed. 1 suffruticosol A, 2 suffruticosol B, 3 suffruticosol C, 4 trans-resveratrol, 5 cis-Îľ-viniferin, 6 trans-Îľ-viniferin, 7 cis-suffruticosol D, 8 cis-gnetin H, 9 trans-suffruticosol D, and 10 trans-gnetin H.
He, Yu-Kun, Cen, Xiao-Tong, Shuang-Shuang Liu, Hua-Ding Lu, Chun-Nian He   +4 more
openaire   +1 more source

Pro-Inflammatory Levels of Interleukin-1α-Like Bioactivity Are Present in the Majority of Open Comedones in Acne Vulgaris

Journal of Investigative Dermatology, 1992
The factors that initiate the inflammatory response in acne are not known. The presence of pro-inflammatory cytokines in acne comedones was therefore investigated. One hundred eight open comedones were collected from 18 untreated acne patients (10 male, 8 female).
Ingham, Eileen, Eady, E Anne, Goodwin, Christina E, Cove, Jonathan H, Cunliffe, William J   +4 more
openaire   +2 more sources

MOESM6 of Protective effects of ten oligostilbenes from Paeonia suffruticosa seeds on interleukin-1β-induced rabbit osteoarthritis chondrocytes

, 2019
Additional file 6. Immunofluorescence of Collagen II to identify primary chondrocytes. The Collagen Type II Antibody (Proteintech, USA) was used as the primary antibody. After the chondrocytes were incubated with goat anti-mouse immunoglobulin Alexa Fluor Plus 594 (1:200 dilution), they were stained red. The nuclei were stained with DAPI. After merging
He, Yu-Kun, Cen, Xiao-Tong, Shuang-Shuang Liu, Hua-Ding Lu, Chun-Nian He   +4 more
openaire   +1 more source

Increased interleukin 1α and interleukin 1β expression is involved in the progression of periapical lesions in primary teeth

BMC Oral Health, 2018
Background Interleukin 1 (IL-1) is involved in bone resorption. However, the role of IL-1 in periapical lesions characterized by periapical bone destruction in primary teeth has not yet been fully elucidated.
Ning-Yan Yang, Yan Zhou, Huan-Ying Zhao, Xiao-Yong Liu, Zheng Sun, Jia-Jian Shang   +5 more
doaj   +1 more source

Deficiency of the purinergic receptor 2X7 attenuates nonalcoholic steatohepatitis induced by high-fat diet. possible role of the NLRP3 Inflammasome [PDF]

, 2017
Molecular mechanisms driving transition from simple steatosis to nonalcoholic steatohepatitis (NASH), a critical step in the progression of nonalcoholic fatty liver disease (NAFLD) to cirrhosis, are poorly defined. This study aimed at investigating the
Blasetti Fantauzzi, Claudia, Iacobini, Carla, Menini, Stefano, Pugliese, Giuseppe, Rossi, Chiara, Santini, Eleonora, Solini, Anna   +6 more
core   +3 more sources

Additional file 1: of Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration

, 2018
Table S1. Sequences of primers used for quantitative real-time polymerase chain reaction experiments. (DOCX 12 kb)
Yu-Chien Guo, Yun-Hsuan Chiu, Chie-Pein Chen, Hwai-Shi Wang   +3 more
openaire   +1 more source

Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production

mBio, 2013
The interaction of Candida albicans with macrophages induces the production of interleukin 1β (IL-1β) through inflammasome activation in a process that is required for host survival. C.
Melanie Wellington, Kristy Koselny, Damian J. Krysan   +2 more
doaj   +1 more source