Results 11 to 20 of about 24,572,041 (402)
Expression of Interleukin-1 and Interleukin-1 Receptors Type 1 and Type 2 in Hodgkin Lymphoma. [PDF]
PLoS ONE, 2015 Signaling through the IL-1-receptor type 1 (IL-1R1), IL-1 is required for initiation and maintenance of diverse activities of the immune system. A second receptor, IL-1R2, blocks IL-1 signal transduction. We studied expression of IL-1beta, IL-1R1, and IL-
Elisabeth Oelmann +3 more
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Beyond an inflammatory mediator: Interleukin‐1 in neurophysiology
Experimental Physiology, 2023 Since its discovery in the early 1940s, the interleukin‐1 (IL‐1) cytokine family has been associated primarily with acute and chronic inflammation. The family member IL‐1β is produced by different leucocytes, endothelial cells and epithelial cells.
Tatiane S. Lima
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Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
Circulation Research, 2020 Supplemental Digital Content is available in the text. The intracellular sensing protein termed NLRP3 (for NACHT, LRR, and PYD domains-containing protein 3) forms a macromolecular structure called the NLRP3 inflammasome.
A. Abbate +5 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 ObjectivesThis study aims to describe the characteristics of patients diagnosed with pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome at a single center in China and provide an up-to-date literature review.MethodsThe clinical data and ...
Yumei Wang +4 more
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Biologic basis for interleukin-1 in disease.
Blood, 1996 To understand the role of the proinflammatory cytokine interleukin-1 (IL-1) in disease, investigators have studied how production of the different members of the IL-1 family is controlled, the various biologic activities of IL-1, the distinct and various
C. Dinarello
semanticscholar +1 more source
Frontiers in Pharmacology, 2017 Background: Mesenchymal stem cells (MSCs) and their chondrogenic differentiation have been extensively investigated in vitro as MSCs provide an attractive source besides chondrocytes for cartilage repair therapies.
Nicole Armbruster +6 more
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Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors
Journal of Neuroinflammation, 2011 Background We have previously outlined functional interactions, including feedback cycles, between several of the gene products implicated in the pathogenesis of Alzheimer's disease.
Liu Ling +5 more
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Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments
Journal of Neuroinflammation, 2020 Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments.
Flora Reverchon +8 more
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Zdorovʹe Rebenka, 2014 The general characteristics of interleukin 1 family is given in the review.
A.Ye. Abaturov +2 more
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Case Report: Therapeutic Use of Ibrutinib in a Patient With Schnitzler Syndrome
Frontiers in Immunology, 2022 Schnitzler syndrome is a rare adult-onset acquired autoinflammatory disorder typically characterized by chronic urticarial rash and immunoglobulin M (IgM) (rarely IgG) monoclonal gammopathy.
Yuehua Huang +6 more
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