Results 21 to 30 of about 703,665 (265)

Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer

Frontiers in Pharmacology, 2017
Background: Mesenchymal stem cells (MSCs) and their chondrogenic differentiation have been extensively investigated in vitro as MSCs provide an attractive source besides chondrocytes for cartilage repair therapies.
Nicole Armbruster, Nicole Armbruster, Jennifer Krieg, Jennifer Krieg, Manuel Weißenberger, Carsten Scheller, Andre F. Steinert   +6 more
doaj   +1 more source

Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments

Journal of Neuroinflammation, 2020
Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments.
Flora Reverchon, Vidian de Concini, Vanessa Larrigaldie, Sulayman Benmerzoug, Sylvain Briault, Dieudonnée Togbé, Bernhard Ryffel, Valérie F. J. Quesniaux, Arnaud Menuet   +8 more
doaj   +1 more source

Involvement of Interleukin 1 Family in the Development of Inflammatory Response in the Infectious Process. 1. General Description of Interleukin 1 Family

Zdorovʹe Rebenka, 2014
The general characteristics of interleukin 1 family is given in the review.
A.Ye. Abaturov, A.P. Volosovets, Ye.I. Yulish   +2 more
doaj   +1 more source

Neuroinflammation Associated With Inborn Errors of Immunity

Frontiers in Immunology, 2022
The advent of high-throughput sequencing has facilitated genotype-phenotype correlations in congenital diseases. This has provided molecular diagnosis and benefited patient management but has also revealed substantial phenotypic heterogeneity.
Hannes Lindahl, Hannes Lindahl, Yenan T. Bryceson, Yenan T. Bryceson, Yenan T. Bryceson   +4 more
doaj   +1 more source

Modern and Convensional Wound Dressing to Interleukin 1 and Interleukin 6 in Diabetic wound

Jurnal Ners, 2015
Introduction:Holistic wound care is one of the ways to prevent gangrene and amputation, modern wound dressing is more effective than convensional with increasing transforming growth factor and cytokine, especially interleukin. This study aims to identify
Werna Nontji, Suni Hariati, Rosyidah Arafat   +2 more
doaj   +1 more source

Presence of interleukin-8 and the IL-1 receptor antagonist in the cervical mucus of fertile and infertile women [PDF]

Vojnosanitetski Pregled, 2004
Background. Cytokines are involved in almost every aspect of reproduction and recent studies suggested a relationship between cytokines and male/female infertility.
Kataranovski Milena, Radojčić Ljiljana, Prokić Vera, Vojvodić Danilo   +3 more
doaj   +1 more source

Interleukin-1 and Systemic Sclerosis: Getting to the Heart of Cardiac Involvement

Frontiers in Immunology, 2021
Systemic sclerosis (SSc) is rare, severe connective tissue disease characterized by endothelial and vascular damage, immune activation, and resulting in inflammation and fibrosis of skin and internal organs, including the heart.
Giacomo De Luca, Giacomo De Luca, Giulio Cavalli, Giulio Cavalli, Corrado Campochiaro, Corrado Campochiaro, Cosimo Bruni, Alessandro Tomelleri, Alessandro Tomelleri, Lorenzo Dagna, Lorenzo Dagna, Marco Matucci-Cerinic   +11 more
doaj   +1 more source

Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease

Frontiers in Immunology, 2022
IntroductionTherapeutic options are critically needed for children with refractory very early onset inflammatory bowel disease (VEO-IBD). Our aim was to evaluate clinical response to canakinumab, an anti-IL-1β monoclonal antibody, in patients with VEO ...
Eliana Shaul, Máire A. Conrad, Máire A. Conrad, Noor Dawany, Trusha Patel, Trusha Patel, Megan C. Canavan, Alyssa Baccarella, Sarah Weinbrom, Daniel Aleynick, Kathleen E. Sullivan, Kathleen E. Sullivan, Judith R. Kelsen, Judith R. Kelsen   +13 more
doaj   +1 more source

IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19

Journal of Innate Immunity, 2022
Acute respiratory distress syndrome (ARDS) in COVID-19 has been associated with catastrophic inflammation. We present measurements in humans and a new animal model implicating a role in danger-associated molecular patterns.
Georgios Renieris, Eleni Karakike, Theologia Gkavogianni, Dionysia-Eirini Droggiti, Emmanouil Stylianakis, Theano Andriopoulou, Victoria-Marina Spanou, Dionyssios Kafousopoulos, Mihai G. Netea, Jesper Eugen-Olsen, John Simard, Evangelos J. Giamarellos-Bourboulis   +11 more
doaj   +1 more source

Safety and efficacy of canakinumab treatment for undifferentiated autoinflammatory diseases: the data of a retrospective cohort two-centered study

Frontiers in Medicine, 2023
IntroductionThe blockade of interleukine-1 (anakinra and canakinumab) is a well-known highly effective tool for monogenic autoinflammatory diseases (AIDs), such as familial Mediterranean fever, tumor necrosis factor receptor-associated periodic syndrome,
Ekaterina Alexeeva, Ekaterina Alexeeva, Meiri Shingarova, Meiri Shingarova, Tatyana Dvoryakovskaya, Tatyana Dvoryakovskaya, Olga Lomakina, Anna Fetisova, Ksenia Isaeva, Aleksandra Chomakhidze, Kristina Chibisova, Elizaveta Krekhova, Aleksandra Kozodaeva, Kirill Savostyanov, Aleksandr Pushkov, Ilya Zhanin, Dmitry Demyanov, Evgeny Suspitsin, Evgeny Suspitsin, Konstantin Belozerov, Mikhail Kostik   +20 more
doaj   +1 more source