Results 11 to 20 of about 703,665 (265)
Modulation of adult hippocampal neurogenesis by interleukin 1 signaling [PDF]
Neurobiology of Sleep and Circadian RhythmsAdult hippocampal neurogenesis (AHN) plays a critical role in cognition and emotional regulation. Recent studies have linked compromised AHN to numerous neurological and psychological disorders.
Maria I. Smirnova, Ning Quan
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Open Biology, 2022 The cytokine interleukin 1 (IL-1) is an evolutionary innovation of vertebrates. Fish and amphibian have one IL1 gene, while mammals have two copies of IL1, IL1A and IL1B, with distinct expression patterns and differences in their proteolytic activation ...
Eva Hasel de Carvalho +4 more
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Applied Sciences, 2022 Recent studies report that individuals with polymorphisms in the genes that encode for interleukin (IL)-1α and IL-1β (IL-1A and IL1B, respectively) and for IL-1 receptor antagonist (IL-1RN) may be more susceptible in developing peri-implantitis ...
José Maria Cardoso +5 more
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Emerging Therapies for Recurrent Pericarditis: Interleukin‐1 inhibitors
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Recurrent pericarditis (RP) is a complex inflammatory disorder associated with adverse outcomes and poor quality of life. After the first episode of acute pericarditis, a non‐negligible group of patients will fail to achieve complete remission despite ...
Saberio Lo Presti +5 more
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Disease Activity Is More Associated with IL-1 Than with IL-6 in Patients with Rheumatoid Arthritis
Life, 2022 Interleukin-1 receptor antagonist (IL-1ra) concentration reflects and is proportional to IL-1 production. Both IL-1 and IL-6 are involved in the pathogenesis of rheumatoid arthritis (RA).
Cristina Almeida-Santiago +6 more
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Beyond an inflammatory mediator: Interleukin‐1 in neurophysiology
Experimental Physiology, 2023 Since its discovery in the early 1940s, the interleukin‐1 (IL‐1) cytokine family has been associated primarily with acute and chronic inflammation. The family member IL‐1β is produced by different leucocytes, endothelial cells and epithelial cells.
Tatiane S. Lima
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Expression of Interleukin-1 and Interleukin-1 Receptors Type 1 and Type 2 in Hodgkin Lymphoma. [PDF]
PLoS ONE, 2015 Signaling through the IL-1-receptor type 1 (IL-1R1), IL-1 is required for initiation and maintenance of diverse activities of the immune system. A second receptor, IL-1R2, blocks IL-1 signal transduction. We studied expression of IL-1beta, IL-1R1, and IL-
Elisabeth Oelmann +3 more
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Interleukin-1 and interleukin-1 antagonism [PDF]
Blood, 1991 The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes.
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Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors
Journal of Neuroinflammation, 2011 Background We have previously outlined functional interactions, including feedback cycles, between several of the gene products implicated in the pathogenesis of Alzheimer's disease.
Liu Ling +5 more
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