Results 41 to 50 of about 28,282,310 (344)
Frontiers in Medicine, 2023 IntroductionThe blockade of interleukine-1 (anakinra and canakinumab) is a well-known highly effective tool for monogenic autoinflammatory diseases (AIDs), such as familial Mediterranean fever, tumor necrosis factor receptor-associated periodic syndrome,
Ekaterina Alexeeva +20 more
doaj +1 more source
Influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training on the plasma cytokine response to maximum sustainable voluntary ventilation [PDF]
, 2014 The influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training (IMT) on the cytokine response to maximum sustainable voluntary ventilation (MSVV) is unknown.
Brown PI +10 more
core +1 more source
Targeting RIP Kinases in Chronic Inflammatory Disease
Biomolecules, 2021 Chronic inflammatory disorders are characterised by aberrant and exaggerated inflammatory immune cell responses. Modes of extrinsic cell death, apoptosis and necroptosis, have now been shown to be potent drivers of deleterious inflammation, and mutations
Mary Speir +4 more
doaj +1 more source
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
, 2016 Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
core +1 more source
Change in Eosinophil Count in Patients with Heart Failure Treated with Anakinra
Cells, 2023 Background: Interleukin-1 blockade with anakinra leads to a transient increase in eosinophil blood count (eosinophils) in patients with acute myocardial infarction. We aimed to investigate the effect of anakinra on changes in eosinophils in patients with
Michele Golino +17 more
doaj +1 more source
Interleukin-1 Beta—A Friend or Foe in Malignancies?
International Journal of Molecular Sciences, 2018 Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation.
R. Bent +3 more
semanticscholar +1 more source
Evidence of Massive Horizontal Gene Transfer Between Humans and Plasmodium vivax [PDF]
, 2011 The horizontal transfer of DNA between different organisms is a major force shaping the genomes of prokaryotes, but is considered to have a minor role in eukaryotes, with only a handful of known examples, mostly of limited size.
Daniel Z. Bar
core +2 more sources
The Legacy of Sickness Behaviors
Frontiers in Psychiatry, 2020 Systemic infections of all types lead to a syndrome known as sickness behaviors. Changes in the behavior of febrile humans and animals formed the original basis for this concept.
Keith W. Kelley +4 more
doaj +1 more source
Inflammasome signaling and regulation of interleukin-1 family cytokines
Journal of Experimental Medicine, 2019 Specific IL-1 family cytokines are initially expressed as inactive, cytosolic pro-forms. Chan and Schroder review inflammasome signaling and cell death decisions, mechanisms underpinning IL-1α, IL-1β, IL-18, and IL-37 maturation and release, and the ...
A. Chan, K. Schroder
semanticscholar +1 more source
Growth factors and experimental arterial grafts [PDF]
, 2016 Background: The production of growth factors from several experimental arterial conduits was determined. Methods: We implanted 105 experimental arterial grafts that were 1 cm long in the abdominal aorta of Lewis rats (average weight, 250 g).
BORRELLI, Valeria +6 more
core +1 more source