Results 21 to 30 of about 24,572,041 (402)

Human interleukin-1 receptor antagonist is expressed in liver [PDF]

, 1992
Using PCR and Northern blot analysis, an IL-1 receptor antagonist specific transcript was amplified from HepG2- and liver mRNA, cDNA clones coding for IL-1 receptor antagonist were isolated from a liver cDNA library and sequence comparison revealed ...
Estaller, C., Sim, Robert B., Steinkasserer, Alexander, Weiss, Elisabeth H.   +3 more
core   +1 more source

Modern and Convensional Wound Dressing to Interleukin 1 and Interleukin 6 in Diabetic wound

Jurnal Ners, 2015
Introduction:Holistic wound care is one of the ways to prevent gangrene and amputation, modern wound dressing is more effective than convensional with increasing transforming growth factor and cytokine, especially interleukin. This study aims to identify
Werna Nontji, Suni Hariati, Rosyidah Arafat   +2 more
doaj   +1 more source

The effect of statin administration on IL-6 and IL-1b expression in peripheral blood mononuclear cells of a hypertensive patient with SARS-CoV-2 spike protein stimulation [PDF]

Medicinski Glasnik, 2022
Aim The infection of the SARS-CoV-2 virus potentially causes a cytokine storm with elevated IL-6 and IL-1β levels. Statin therapy was common among COVID-19 patients due to their cardiovascular comorbidities.
Andrianto Andrianto, Budi Susetyo Pikir, Rizki Amalia, Teuku Yusrizal, Fatimah Alzahra, Maya Qurota A’yun, Michael Jonatan   +6 more
doaj   +1 more source

Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]

, 2017
BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat, Jobe, Alan H, Kallapur, Suhas G, Kannan, Paranthaman Senthamarai, Kemp, Matthew W   +4 more
core   +3 more sources

Primary cilia elongation in response to interleukin-1 mediates the inflammatory response [PDF]

, 2012
Primary cilia are singular, cytoskeletal organelles present in the majority of mammalian cell types where they function as coordinating centres for mechanotransduction, Wnt and hedgehog signalling. The length of the primary cilium is proposed to modulate
A. K. T. Wann, AC Lin, AJ Espanol, AM Malone, BD Engel, BK Yoder, CA Dinarello, CG Jensen, CM Asleson, D Qian, DA Lee, E Verghese, E Verghese, EJ Michaud, EM Mokrzan, GJ Pazour, H Tukachinsky, I Memon, J Kim, JA Deane, JL Rosenbaum, JM Neugebauer, K Gardner, KJ Palmer, L Schneider, M Barzi, M Cao, M. M. Knight, MA Lancaster, MB Hovater, N Sharma, P Tummala, PA Lefebvre, PV Tran, RY Kwon, S Abdul-Majeed, S Agarwal, S Kim, S Massinen, S Mukhopadhyay, S Pritchard, S Toffoli, SC Goetz, SM Nauli, SR McGlashan, SR McGlashan, SR McGlashan, TT Chowdhury, TY Besschetnova, Y Chen, Y Ou, YH Choi   +51 more
core   +2 more sources

Interleukin-1 Beta—A Friend or Foe in Malignancies?

International Journal of Molecular Sciences, 2018
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation.
R. Bent, L. Moll, S. Grabbe, Matthias Bros   +3 more
semanticscholar   +1 more source

Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]

, 2018
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu, A Franceschini, AA Culbert, AJ Sharp, AL Giuliani, AM Van Dam, B Sperlágh, C Gabay, C Marinelli, C Solà, C Volonté, CA Dinarello, CM Uhlar, D Ferrari, D Kim, DL Thiele, E Gruys, E Nishida, E Venereau, G Guillemin, G Ristori, H Yokote, I Hardardóttir, I Kushner, I Rajkovic, J Saura, JA Sloane, JS Liang, JT Guo, K Chang, K Niemi, K Selmaj, L Facci, L Facci, L Peferoen, L Probert, L Sun, L Yao, Laura Facci, LK Parvathenani, M Barbierato, M Barbierato, M Casula, M Connolly, M De Buck, M Idzko, M Li, M Sanz, Massimo Barbierato, ME Hamby, MK McCoy, Morena Zusso, MS Kindy, MT Heneka, N Chauvet, N Cheng, P Honore, Pietro Giusti, R Ebert, RA Dal Canto, RJ Rodrigues, S Kim, S Sandri, S Tanaka, SD Skaper, SD Skaper, SD Skaper, SJ Crocker, SJ Hewett, SL Passey, SM Allan, Stephen D. Skaper, SY Seong, T Kawamoto, T Miida, T Tamamoto, TF Chung, TH Holm, XQ Li, Y Kumon, Y Wang, Y Yu, YR Ji   +82 more
core   +2 more sources

Emerging Molecular Targets for the Treatment of Refractory Sarcoidosis

Frontiers in Medicine, 2020
Sarcoidosis is a multisystem granulomatous disease of unknown origin that has variable clinical course and can affect nearly any organ. It has a chronic course in about 25% of patients.
Gonçalo Boleto, Gonçalo Boleto, Matheus Vieira, Matheus Vieira, Anne Claire Desbois, Anne Claire Desbois, Anne Claire Desbois, Anne Claire Desbois, Anne Claire Desbois, David Saadoun, David Saadoun, David Saadoun, David Saadoun, David Saadoun, Patrice Cacoub, Patrice Cacoub, Patrice Cacoub, Patrice Cacoub, Patrice Cacoub   +18 more
doaj   +1 more source

An interleukin-1 polymorphism additionally intensified by atopy as prognostic factor for aseptic non-mechanical complications in metal knee and hip arthroplasty

Frontiers in Immunology, 2022
BackgroundIn contrast to infection or mechanical issues joint replacement failure following inflammatory adverse reactions is poorly understood.ObjectiveTo assess the association of IL-1β polymorphisms and history of allergy with aseptic non-mechanical ...
B. Summer, D. Lill, K. Remmel, A. Schraml, C. Schopf, I. J. Banke, H. Kuechenhoff, T. Maierhofer, S. Endres, P. Thomas   +9 more
doaj   +1 more source

Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis

Frontiers in Cellular and Infection Microbiology, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) represents the etiological agent for several human malignancies, including Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD), which are mostly seen in ...
Lindsey Barrett, Jungang Chen, Lu Dai, Karlie Plaisance-Bonstaff, Luis Del Valle, Zhiqiang Qin   +5 more
doaj   +1 more source