Results 31 to 40 of about 10,723,036 (376)

The Interleukin-10 Family of Cytokines and Their Role in the CNS

open access: yesFrontiers in Cellular Neuroscience, 2018
Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient,
Amanda R Burmeister, I. Marriott
semanticscholar   +1 more source

Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures

open access: yesJournal of Neuroinflammation, 2019
Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system. Interleukin (IL)-10 and IL-1β secreted by glial cells support neuronal functions, but the related mechanisms remain vague.
Yi Sun   +9 more
semanticscholar   +1 more source

β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. [PDF]

open access: yes, 2020
Background & aimsIntegrin α4β7 mediates lymphocyte trafficking to the gut and gut-associated lymphoid tissues, a process critical for recruitment of effector lymphocytes from the circulation to the gut mucosa in inflammatory bowel disease (IBD) and ...
Eckmann, Lars   +5 more
core   +1 more source

Cytokine profiling for Egyptian diabetic patients with nephropathy

open access: yesJournal of Medicine in Scientific Research, 2022
Background Evidence suggests that poor glycemic control is significantly associated with the development of microvascular complications of diabetes such as nephropathy.
Samar M Samir   +3 more
doaj   +1 more source

Mapping of the interleukin‐10/interleukin‐10 receptor combining site [PDF]

open access: yesProtein Science, 1998
AbstractThe discontinuous interleukin‐10(IL‐10)/interleukin‐10 receptor (IL‐10R) combining site was mapped using sets of overlapping peptides derived from both binding partners bound to continuous cellulose membranes. Low affinity binding of single regions of the discontinuous contact sites on IL‐10 and IL‐10R could be identified due to (1) high ...
U, Reineke   +3 more
openaire   +2 more sources

Current review of genetically modified lactic acid bacteria for the prevention and treatment of colitis using murine models [PDF]

open access: yes, 2015
Inflammatory Bowel Diseases (IBD) are disorders of the gastrointestinal tract characterized by recurrent inflammation that requires lifelong treatments.
Azevedo, Vasco   +7 more
core   +1 more source

Role of Interleukin-10 in Acute Brain Injuries

open access: yesFrontiers in Neurology, 2017
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged causes secondary brain damage.
Joshua M. Garcia   +8 more
semanticscholar   +1 more source

Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]

open access: yes, 2018
Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena   +3 more
core   +3 more sources

The Correlation between Interleukin-10 Serum with Bacterial Index in Multidrug Therapy-treated Leprosy Patients

open access: yesBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Immune respons disturbance oftenly found in leprosy patient, mainly in various T cell subset and cytokine immune system arranger. Interleukin-10 produced by Th 2 cell, Th3 cell, monocyte, dendritic cell, eosinophil, mast cell, and ...
Eva Krishna Sutedja   +2 more
doaj   +1 more source

Interleukin‐10 responses from acute exercise in healthy subjects: A systematic review

open access: yesJournal of Cellular Physiology, 2018
Interleukin 10 (IL‐10) is a cytokine that plays a critical role with potent anti‐inflammatory properties when produced during exercise, limiting host immune response to pathogens and preventing tissue damage.
C. Cabral-Santos   +6 more
semanticscholar   +1 more source

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