Results 1 to 10 of about 628,016 (161)
Plasma interleukin-12 levels as a potential biomarker of fatigue and quality of life in patients with primary immune thrombocytopenia [PDF]
Blood ResearchBackground Fatigue significantly affects health-related quality of life (HRQoL) in patients with immune thrombocytopenia (ITP). However, the interplay between fatigue and cytokines in ITP remains poorly understood.
Sarthak Wadhera +12 more
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Atomic Pt-Layer-Coated Au Peroxidase Nanozymes with Enhanced Activity for Ultrasensitive Colorimetric Immunoassay of Interleukin-12 [PDF]
BiosensorsInterleukin-12 (IL-12), a crucial biomarker for immune and inflammatory responses, plays a pivotal role in diagnosing and managing diverse pathological conditions.
Han Zhang +6 more
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Tumor-specific AAV delivery of interleukin-12 enhances antitumor immunity and safety in ovarian cancer xenograft mouse model [PDF]
Molecular Therapy: OncologyInterleukin-12 (IL-12) is a promising pro-inflammatory cytokine for cancer immunotherapy, but its toxicity and short half-life in serum limit its clinical application.
Chuyuan Chen +6 more
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Научно-практическая ревматология, 2022 Among the pathophysiological mechanisms of immune-mediated inflammatory diseases (IMIDs), specific attention has been paid to the abnormal activation of Th17 type immune response related to the dysregulated synthesis of cytokines forming the interleukin (
E. L. Nasonov +3 more
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BMC Medical Genetics, 2020 Background Intervertebral disc degeneration (IVDD) is an age-related degenerative disease, presenting with low back pain or radicular pain. The inflammatory changes would occur in discs in the process of IVDD.
Sara Hanaei +6 more
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Iranian Journal of Parasitology, 2020 Background: The possible risk factor of Toxoplasma infection and its possible correlation with Interleukin-12 (IL-12) and Interleukin-23 (IL-23) in breast cancer patients was investigated. Methods: Overall, 190 female patients referred to the Oncology
Maha Mustafa ASSIM, Entsar Jabbar SAHEB
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The Role of Interleukin 12 in Iraqi Patients with Psoriasis
مجلة علوم ذي قار, 2022 Psoriasis is a chronic skin condition with immune-mediated inflammatory etiology. Many studies have indicated that Interleukin-12 (IL-12) plays an essential role in the severity of psoriasis.So to elucidate IL-12 role in regulating psoriasis promotion ...
Emad A. Abbas, Hind M Mousa
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Peripheral Helper Lymphocytes Produce Interleukin 12 in Cancer Patients
Clinical Medicine Insights: Oncology, 2013 The aim of the study was to seek evidence for the production of IL-12 by CD4 + T lymphocytes in in vitro and ex vivo trials. We performed in vitro trials with spleen cells from mice subjected to carcinogenesis, as well as ex vivo trials with cells ...
Márcia A. Michelin +3 more
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Factors Associated With In Vitro Interferon-gamma Production in Tuberculosis
Journal of the Formosan Medical Association, 2011 Macrophage activation assisted by interferon-gamma (IFN-γ) is a primary mechanism by which Mycobacterium tuberculosis is killed, but IFN-γ (production is inhibited in tuberculosis (TB) patients. The production of IFN-γ is influenced by many factors, such
Chung-Chieh Yu +5 more
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Regulation of NK cell development and function by cytokines
Frontiers in Immunology, 2013 Natural Killer (NK) cells are innate lymphocytes with an important role in the early defense against intracellular pathogens and against tumors. Like other immune cells, almost every aspects of their biology are regulated by cytokines.
Antoine eMarçais +5 more
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