Results 1 to 10 of about 563,024 (285)

Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]

open access: goldACR Open Rheumatology
Giant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest   +4 more
doaj   +4 more sources

The parasitic helminth product ES‐62 suppresses pathogenesis in collagen‐induced arthritis by targeting the interleukin‐17–producing cellular network at multiple sites [PDF]

open access: bronze, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Miguel A. Pineda   +7 more
openalex   +4 more sources

IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]

open access: yesBrazilian Oral Research, 2023
Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE   +6 more
doaj   +1 more source

Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]

open access: yesCell Communication and Signaling
Background We previously identified Il17RB, a member of the IL17 superfamily, as a candidate marker gene for endometrial aging. While IL17RB has been linked to inflammation and malignancies in several organ systems, its function in the endometrium has ...
Keiko Kawamura   +9 more
doaj   +2 more sources

Levels of IL-23/IL-17 Axis in Plasma and Gingival Tissue of Periodontitis Patients According to the New Classification

open access: yesApplied Sciences, 2022
Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño   +7 more
doaj   +1 more source

Interleukin 17 in early invasive breast cancer

open access: yesFrontiers in Oncology, 2023
IntroductionInterleukin 17 (IL-17) has a key role in inflammatory responses. Increased serum concentrations of IL-17 have been reported in patients with different types of cancer.
Marina Popović   +9 more
doaj   +1 more source

Role of Interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression [PDF]

open access: yes, 2010
Background: The use of TNF inhibitors has been a major progress in the treatment of chronic inflammation. However, not all patients respond. In addition, response will be often lost when treatment is stopped. These clinical aspects indicate that other
A Maitra   +58 more
core   +17 more sources

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen   +3 more
doaj   +1 more source

Relationship between interleukin 17 & 6 in patients with varicocele compare with a control group [PDF]

open access: yesJournal of Medical and Life Science, 2019
The spermatogenesis process is very complex and involves many processes that lead to giving normal sperm, these sperms are very important for Fertility in the male.
Hayder AL-Msaid, Waleed H., Hydar Khalfa
doaj   +1 more source

Dramatic secukinumab-mediated improvements in refractory leprosy-related neuritis via the modulation of T helper 1 (Th1) and T helper 17 (Th17) immune pathways

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2021
A 39-year-old woman was diagnosed with relapsed multibacillary leprosy and refractory neuritis. Here, we describe an evident loss of therapeutic effectiveness after the third pulse of corticosteroids, which may be attributed to tachyphylaxis and the ...
Patrícia Shu Kurizky   +6 more
doaj   +1 more source

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