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Roles of interleukin-17 in uveitis [PDF]
Indian Journal of Ophthalmology, 2016 Th17 cells, a CD4+ T-cell subset, produce interleukin (IL)-17, a pro-inflammatory cytokine that has been shown to be involved in several forms of infectious and noninfectious uveitis.
Marta Catarina Esteves Guedes +2 more
doaj +5 more sources
Interleukin-17 in Antifungal Immunity [PDF]
Pathogens, 2019 The field of IL-17 biology has received much attention over the last decade owing to the pathogenic role of this cytokine in psoriasis and other autoinflammatory disorders and the successful implementation of IL-17-targeting therapies in patients ...
Florian Sparber +1 more
doaj +6 more sources
Role of Interleukin-17 in Acute Pancreatitis [PDF]
Frontiers in Immunology, 2021 Acute pancreatitis (AP) is a leading cause of death and is commonly accompanied by systemic manifestations that are generally associated with a poor prognosis. Many cytokines contribute to pancreatic tissue damage and cause systemic injury.
Guanqun Li +11 more
semanticscholar +5 more sources
Interleukin‐17 and ischaemic stroke [PDF]
Immunology, 2020 Interleukin‐17 (IL‐17) is a cytokine family that includes 6 members, IL‐17A through IL‐17F, most of them are reported to have pro‐inflammatory role. Through binding to their receptors (IL‐17Rs), IL‐17 activates the intracellular signalling pathways to ...
Qiaohui Zhang +6 more
semanticscholar +4 more sources
Bioscience, Biotechnology, and Biochemistry, 2023 This research is based on a systematic evolution of ligands by exponential enrichment (SELEX), also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA).
Arifur Rahman Munshi +10 more
semanticscholar +3 more sources
Interleukin 17 in early invasive breast cancer [PDF]
Frontiers in Oncology, 2023 IntroductionInterleukin 17 (IL-17) has a key role in inflammatory responses. Increased serum concentrations of IL-17 have been reported in patients with different types of cancer.
Marina Popović +9 more
doaj +2 more sources
Interleukin-17 family members and inflammation. [PDF]
Immunity, 2004 IL-17A was cloned more than 10 years ago and six IL-17 family members (IL-17A-F) have subsequently been described. IL-17A is largely produced by activated memory T lymphocytes but stimulates innate immunity and host defense. IL-17A and IL-17F both mobilize neutrophils partly through granulopoeisis and CXC chemokine induction, as well as increased ...
J. Kolls, A. Lindén
semanticscholar +3 more sources
Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis [PDF]
BMC Medical Genomics, 2023 Background The pathogenesis of rheumatoid arthritis (RA) is an immune imbalance, in which various inflammatory immune cells and pro-inflammatory factors are involved.
Rong Zhao +7 more
doaj +2 more sources
Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]
Cell Communication and SignalingBackground We previously identified Il17RB, a member of the IL17 superfamily, as a candidate marker gene for endometrial aging. While IL17RB has been linked to inflammation and malignancies in several organ systems, its function in the endometrium has ...
Keiko Kawamura +9 more
doaj +2 more sources
IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]
Brazilian Oral Research, 2023 Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE +6 more
doaj +1 more source