Results 51 to 60 of about 3,159,504 (378)
CCR2⁺CD103⁻ intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells [PDF]
, 2014 The identification of intestinal macrophages (m phi s) and dendritic cells (DCs) is a matter of intense debate. Although CD103(+) mononuclear phagocytes (MPs) appear to be genuine DCs, the nature and origins of CD103(-) MPs remain controversial.
Agace, WW +11 more
core +3 more sources
The Treatment with Interleukin 17 Inhibitors and Immune-Mediated Inflammatory Diseases
Current Issues in Molecular Biology, 2022 IL-17 inhibitors (IL-17i) are medicines used to treat dermatological and rheumatic diseases They belong to a class of medicines called biological disease-modifying anti-rheumatic drugs (bDMARDs).
Laura Țiburcă +6 more
doaj +1 more source
The Role of Interleukin-17 in Lung Cancer [PDF]
Mediators of Inflammation, 2016 Tumour-associated inflammation is a hallmark of malignant carcinomas, and lung cancer is a typical inflammation-associated carcinoma. Interleukin-17 (IL-17) is an important inflammatory cytokine that plays an important role in chronic inflammatory and autoimmune diseases and in inflammation-associated tumours.
Feng Wu +13 more
openaire +4 more sources
γδ T Cell Selection: Is Anyone Useless? [PDF]
, 2008 In this issue of Immunity, a study by Jensen et al. (2008) suggests that T cell-receptor engagement during development affects γδ T cell polarization toward either interferon-γ or interleukin-17 production. This might underlie their unique innate ability
Bonneville, Marc
core +1 more source
Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma
Advanced Biomedical Research, 2014 Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani +4 more
doaj +1 more source
Is interleukin-17 implicated in early knee osteoarthritis pathogenesis as in rheumatoid arthritis?
Egyptian Rheumatology and Rehabilitation, 2022 Background Interleukin-17 (IL-17) is a cytokine that promotes activation of multiple catabolic pathways resulting in cartilage and tissue damage. It has features making it increasingly attractive as a biological marker, especially in rheumatoid arthritis
Hoda M. Abdel-Naby +3 more
doaj +1 more source
Effectiveness and Safety of Anti-interleukin-17 Therapies in Elderly Patients with Psoriasis
Acta Dermato-Venereologica, 2020 Anti-interleukin-17 agents have recently been developed for the treatment of psoriasis. This study evaluated the tolerance and effectiveness of anti-interleukin-17 agents for psoriasis in elderly patients in daily practice.
C. Phan +31 more
semanticscholar +1 more source
Interleukin-17 in human inflammatory diseases [PDF]
Advances in Dermatology and Allergology, 2014 Human Th17 pro-inflammatory cells are currently defined as cells that produce IL-17A and F, tumor necrosis factor (TNF)-α, IL-6, IL-21, IL-22 and IL-23. Recently discovered related molecules are forming a family of cytokines, the IL-17 family, IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F.
Ebrahim Fattahi +2 more
openaire +3 more sources
Impaired interferon-γ responses, increased interleukin-17 expression, and a tumor necrosis factor–α transcriptional program in invasive aspergillosis [PDF]
, 2009 This article is available open access through the publisher’s website. Copyright @ 2009 Oxford University Press.Background - Invasive aspergillosis (IA) is the most common cause of death associated with fungal infection in the developed world ...
Armstrong-James, DP +7 more
core +1 more source
Frontiers in Immunology, 2020 Osteoarthritis (OA), which is the most common degenerative joint disorder, has been considered a non-inflammatory disease with abnormal mechanics. Interleukin (IL)-17 is a pleiotropic cytokine involved in inflammatory diseases and their production is ...
H. Na +8 more
semanticscholar +1 more source