Results 61 to 70 of about 563,024 (285)
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Interleukin 17 enhances bone morphogenetic protein-2-induced ectopic bone formation
Scientific Reports, 2018 Interleukin 17 (IL-17) stimulates the osteogenic differentiation of progenitor cells in vitro through a synergy with bone morphogenetic protein (BMP)-2. This study investigates whether the diverse responses mediated by IL-17 in vivo also lead to enhanced
M. Croes +6 more
doaj +1 more source
Interaction of Interleukin-17A with a Th2 Response in a Mouse Model of Allergic Airway Inflammation
Cells, 2023 Background: A total of 262 million people worldwide suffer from asthma and 461000 people died from it in 2019. Asthma is a disease with different endotypes defined by the granulocytes found in the asthmatic lung.
Karin Peters +2 more
doaj +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. [PDF]
, 2007 Peroxisome proliferator-activated receptor (PPAR)alpha is a nuclear receptor that mediates gender differences in lipid metabolism. PPARalpha also functions to control inflammatory responses by repressing the activity of nuclear factor kappaB (NF-kappaB ...
Baranzini, Sergio E +9 more
core
Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells [PDF]
, 2017 Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA.
Aya Castañeda, Maria del Rosario +6 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Consilium MedicumAim. To evaluate the clinical efficacy and safety of netakimab (an interleukin-17 inhibitor) in hospitalized patients with severe COVID-19. Materials and methods. A retrospective case-control study was conducted involving 171 patients. The main group (
Zamira M. Merzhoeva +7 more
doaj +1 more source
Autoimmunity, 2018 A characteristic feature of primary Sjögren’s syndrome (pSS) is the destruction of salivary and lacrimal glands mediated by mononuclear cell infiltration.
Lara A. Aqrawi +8 more
doaj +1 more source
Investigating the Effect of Endurance Training on Tumor Level of IL-8 and Serum Level of IL-17 in Female Mice with Breast Cancer [PDF]
Journal of Fasa University of Medical Sciences, 2015 Background & Objectives: Breast cancer is nowadays one of the most harmful threats to women’s health. However, exercise training plays an adjuvant role in breast cancer (Adjuvant also means preventive. So, no need to repeat preventing.). Therefore,
AR Kazemi +6 more
doaj +1 more source