Results 51 to 60 of about 579,902 (183)
Journal of Translational Medicine, 2018 Background The cytokine, interleukin-18 (IL-18), was originally identified as an interferon-γ-inducing proinflammatory factor; however, there is increasing evidence suggesting that it has non-immunological effects on physiological functions.
Kyosuke Yamanishi +14 more
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Clinical & Translational Immunology, 2021 Objective In asthma, genome‐wide association studies have shown that interleukin‐18 (IL‐18) receptor 1 gene (IL‐18R1) and sputum IL‐18 are increased during exacerbations. However, the role of the IL‐18 axis in bronchial epithelial function is unclear. To
Davinder Kaur +4 more
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, 2004 Complementary (antisense) peptide mini-receptor inhibitors are complementary peptides designed to be receptor-surrogates that act by binding to selected surface features of biologically important proteins thereby inhibiting protein-cognate receptor ...
Bhakoo, Ashish +4 more
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Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis [PDF]
, 2011 Introduction There has been no report in the literature of a soluble form of interleukin (IL)-18 receptor α (IL-18Rα). In this study, we evaluated the levels and characteristics of soluble IL-18Rα (sIL-18Rα) in the sera of patients with ...
Satoko Takei +12 more
core +1 more source
Regulation of NK cell development and function by cytokines
Frontiers in Immunology, 2013 Natural Killer (NK) cells are innate lymphocytes with an important role in the early defense against intracellular pathogens and against tumors. Like other immune cells, almost every aspects of their biology are regulated by cytokines.
Antoine eMarçais +5 more
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Interleukin 1-β, Interleukin-1 Receptor Antagonist, and Interleukin 18 in Children with Acute Spontaneous Urticaria [PDF]
, 2013 Very little is known about the role of interleukin-1β (IL-1β) and interleukin-18 (IL-18) in urticaria. Material and Methods. Serum levels of IL-1β, IL-1 receptor antagonist (IL-1RA), and IL-18 were measured in 56 children with urticaria and in 41 healthy
A. Kasperska-Zając +4 more
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Association of IL-4 and IL-18 genetic polymorphisms with atopic dermatitis in Chinese children
Frontiers in Pediatrics, 2023 BackgroundAtopic dermatitis (AD) is a common chronic inflammatory skin disease, adversely affecting nearly 20% of the pediatric population worldwide. Interleukin-4 (IL-4) and interleukin-18 (IL-18) are considered to be involved in the pathogenesis and ...
Jianrong Shi +6 more
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Tissue Cytokine Responses in Canine Visceral Leishmaniasis [PDF]
, 2001 To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with those from 5 uninfected control ...
Courtenay, O. +6 more
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Cancer‐killing, decoy‐resistant interleukin‐18 [PDF]
Immunology & Cell Biology, 2020 A recent paper by Zhou et al. describes a new engineered decoy-resistant interleukin-18 with potent antitumor activity and translational potential for cancer immunotherapy.
Kyohei Nakamura +2 more
openaire +3 more sources
Inflammasomes driven inflammation in lung cancer revisited: a short review
Exploration of Immunology, 2023 Lung cancer is the leading cause of cancer-related deaths worldwide. The main risk factor for lung cancer is exposure to chemicals present in cigarettes and atmospheric pollutants, which, among other mechanisms, can increase the risk of cancer by ...
Vitor Rodrigues da Costa +5 more
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