Results 71 to 80 of about 579,902 (183)

Association of rs1946518 C/A Polymorphism in Promoter Region of Interleukin 18 Gene and Breast Cancer Risk in Iranian Women: A Case-control Study

Iranian Journal of Allergy, Asthma and Immunology, 2019
Breast cancer (BC) is the most frequently diagnosed cancer among women in the world. Genetic polymorphisms in Interleukin (IL) genes are one of the most important risk factors in BC. The aim of this study was to investigate the association of rs1946518 C/
Nazila Fathi Maroufi, Elnaz Aghayi, Hamid Garshasbi, Milad Gholampour Matin, Ahmad Babazadeh Bedoustani, Fatemeh Firouzi Amoudizaj, Saba Hajazimian, Alireza Isazadeh, Sina Taefehshokr, Nima Taefehshokr, Behzad Baradaran   +10 more
doaj   +1 more source

The proinflammatory cytokine interleukin 18 regulates feeding by acting on the bed nucleus of the stria terminalis [PDF]

, 2016
The proinflammatory cytokine IL-18 has central anorexigenic effects and was proposed to contribute to loss of appetite observed during sickness. Here we tested in the mouse the hypothesis that IL-18 can decrease food intake by acting on neurons of the ...
Alboni, Silvia, Benatti, Cristina, Berton, Fulvia, Conti, Bruno, Francesconi, Walter, Mori, Simone, Moroncini, Gianluca, Nguyen, William, S\ue1nchez Alavez, Manuel, Tascedda, Fabio, Zorrilla, Eric   +10 more
core   +1 more source

Serum interleukin-18 and extent of coronary artery disease in unstable angina

ARYA Atherosclerosis, 2018
BACKGROUND: Interleukin-18 (IL-18) is an inflammatory marker with challenging role in atherosclerosis. The present study was carried out aiming to evaluate the association between IL-18 serum level and extent and severity of atherosclerosis among young ...
Masoumeh Sadeghi, Maryam Gheraati, Azam Soleimani, Afshin Amirpour, Marzieh Taheri, Safoura Yazdekhasti, Elham Valikhani   +6 more
doaj   +1 more source

Role of genetic aspect in pathogenesis of atopic dermatitis [PDF]

, 2013
The pathogenesis of atopic dermatitis (AD) is a very complicated process that involves an intricate array of molecules. Nowadays it is generally accepted that cytokines play an important role in the progression of the clinical presentation of atopic ...
Wesserling Martyna
core   +2 more sources

Genetic Polymorphism of Interleukin-18 Gene Promoter Region in Rheumatoid Arthritis Patients from Southern India [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Interleukin-18 (IL-18) is a pro inflammatory cytokine which plays a key role in the acute and chronic inflammatory phases of Rheumatoid Arthritis (RA). The Single Nucleotide Polymorphisms (SNPs) of IL-18 gene promoter region at positions -
Varun Chaithanya Gurram, Sunil Kumar Polipalli, Vijay Kumar Karra, Madhavi Puppala, Sanjeev Kumar Pandey, Seema Kapoor, Ashok Kumar, Sudhakar Godi   +7 more
doaj   +1 more source

Potential protein biomarkers for burning mouth syndrome discovered by quantitative proteomics. [PDF]

, 2017
Burning mouth syndrome (BMS) is a chronic pain disorder characterized by severe burning sensation in normal looking oral mucosa. Diagnosis of BMS remains to be a challenge to oral healthcare professionals because the method for definite diagnosis is ...
Diep, Cynthia, Hu, Shen, Ji, Eoon Hye, Li, Hong, Liu, Tong, Merrill, Robert, Messadi, Diana   +6 more
core   +2 more sources

[Interleukin-18].

Postepy higieny i medycyny doswiadczalnej, 2004
The paper describes the properties of interleukin-18 (IL-18), the cytokine originally designated as interferon-gamma inducing factor (IGIF): its production, structure and receptor (IL-18R) transmitting a signal to the cell. Moreover, it presents recent data on its biological activity.
Marek, Fol, Teresa, Gościcka
openaire   +1 more source

Peripheral Interleukin-18 is negatively correlated with abnormal brain activity in patients with depression: a resting-state fMRI study

BMC Psychiatry, 2022
Background Interleukin-18 (IL-18) may participate in the development of major depressive disorder, but the specific mechanism remains unclear. This study aimed to explore whether IL-18 correlates with areas of the brain associated with depression ...
Xiangdong Du, Siyun Zou, Yan Yue, Xiaojia Fang, Yuxuan Wu, Siqi Wu, Haitao Wang, Zhe Li, Xueli Zhao, Ming Yin, Gang Ye, Hongyan Sun, Xiaochu Gu, Xiaobin Zhang, Zhigang Miao, Jeff Wang Jin, Hanjing Emily Wu, Yansong Liu, Xingshun Xu   +18 more
doaj   +1 more source

Circulating interleukin-18: A specific biomarker for atherosclerosis-prone patients with metabolic syndrome [PDF]

, 2011
Background Metabolic syndrome (MetS) is associated with an increased risk of the development of atherosclerotic cardiovascular disease (CVD). Interleukin-18 (IL-18), which is a pleiotropic proinflammatory cytokine with important regulatory functions in ...
Minako Yamaoka-Tojo, Taiki Tojo, Kazuki Wakaume, Ryo Kameda, Shinji Nemoto, Naonobu Takahira, Takashi Masuda, Tohru Izumi   +7 more
core   +2 more sources

Interleukin-18 in Health and Disease [PDF]

International Journal of Molecular Sciences, 2019
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. Therefore, IL-12
Koubun Yasuda, Kenji Nakanishi, Hiroko Tsutsui   +2 more
openaire   +2 more sources