Results 11 to 20 of about 17,429 (49)

Treatment of refractory chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation with low-dose interleukin-2

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
Refractory chronic graft-versus-host disease (cGVHD) is the complication of allogeneic hematopoietic stem cell transplantation (HCT) that signi ficantly impacts quality of life, may be associated with morbidity and mortality and has limited treatment ...
I. S. Moiseev, E. A. Burmina, Y. A. Tarakanova, Y. R. Zalyalov, A. G. Smirnova, O. V. Pirogova, S. N. Bondarenko, B. V. Afanasyev   +7 more
doaj   +1 more source

Elevations in Liver Transaminases in COVID-19: (How) Are They Related?

Frontiers in Medicine, 2021
Liver involvement in COVID-19 is not yet well-understood, but elevations in liver transaminases have been described to occur in 14–53% of the cases and are more frequently seen in severe disease.
Henrique Pott-Junior, Natália Queiroz Prado Bittencourt, Silvana F. G. Chacha, Rafael Luís Luporini, Rafael Luís Luporini, Marcia Regina Cominetti, Fernanda de Freitas Anibal, Fernanda de Freitas Anibal   +7 more
doaj   +1 more source

Expression of chicken interleukin-2 gene in Pichia methanolica

浙江大学学报. 农业与生命科学版, 2003
Chicken interleukin-2 (chIL-2) is an important cytokine discovered recently. To explore a new approach to the expression of chIL-2 gene in methyltrophic yeast-Pichia methanolica (P.
ZHOU Ji-yong, CHEN Ji-gang, WANG Jin-yong, ZHANG De-yong, ZHENG Xiao-juan   +4 more
doaj   +1 more source

Effects of Moxifloxacin on Human Neutrophil and T-Lymphocyte Functions in Vitro

Pharmaceuticals, 2010
Moxifloxacin is useful in the treatment of respiratory infections, including community-acquired pneumonia, and also shows promise in the treatment of tuberculosis, a clinical setting which necessitates extended administration of this agent.
Ronald Anderson, Riana Cockeran, Charles Feldman, Annette J Theron, Moliehi Potjo   +4 more
doaj   +1 more source

A Novel Technique for the Generation of Substantial Numbers of Functional Resident T Cells from Kidney Tissue

Cells, 2022
Studying functionality and antigen-specificity of resident kidney T cells derived from a kidney biopsy is hampered by the lack of sufficient numbers of T cells obtained by the standard method of enzymatic tissue dissociation.
Michiel G. H. Betjes, Frederique Prevoo, Thierry P. P. van den Bosch, Mariska Klepper, Nicolle H. R. Litjens   +4 more
doaj   +1 more source

Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system

Опухоли женской репродуктивной системы, 2014
Malignant pericardial effusions often arise in patients with breаst cancer and ovarian cancer. Sistem antitumor therapy is uneffective in gen- erally and causes side effects.
K. S. Titov, S. M. Volkov, L. V. Demidov, A. N. Gritsay, N. I. Lazareva, M. V. Kiselevskiy, A. P. Nikolayev   +6 more
doaj   +1 more source

An Antibody Targeting Fibroblast Activation Protein Simultaneously Fused to Interleukin-2 and Tumor Necrosis Factor Selectively Localizes to Neoplastic Lesions

Antibodies, 2023
The delivery of specific cytokine payloads to a neoplastic environment employing antibodies able to selectively accumulate at the tumor site represents an attractive strategy to stimulate an immune response to cancer.
Eleonora Prodi, Claudia Comacchio, Ettore Gilardoni, Cesare Di Nitto, Emanuele Puca, Dario Neri, Roberto De Luca   +6 more
doaj   +1 more source

POSSIBLE CHANGES IN THE CENTRAL HEMODYNAMICS IN PORTAL HYPERTENSION DUE TO LIVER CIRRHOSIS OF VIRAL ETIOLOGY WITH DIFFERENT LEVELS OF CYTOKINES

Рациональная фармакотерапия в кардиологии, 2017
Aim. To study possible variants of changes in structural and functional parameters of central hemodynamics in liver cirrhosis classes A, B, C (Child– Pugh) to improve the early diagnostics of extrahepatic complications.Material and methods. Parameters of
V. E Kulikov, T. A. Emelina, O. G. Kazakova, K. V. Nikolaevа, M. E. Hapman, M. A. Tonеeva   +5 more
doaj   +1 more source

Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population

BMC Medical Genetics, 2020
Background Intervertebral disc degeneration (IVDD) is an age-related degenerative disease, presenting with low back pain or radicular pain. The inflammatory changes would occur in discs in the process of IVDD.
Sara Hanaei, Sina Abdollahzade, Maryam Sadr, Mohammad Hossein Mirbolouk, Ehsan Fattahi, Alireza Khoshnevisan, Nima Rezaei   +6 more
doaj   +1 more source

Development of Type 1 Diabetes in Mice Is Associated with a Decrease in IL-2-Producing ILC3 and FoxP3⁺ Treg in the Small Intestine

Molecules, 2023
Recent data indicate the link between the number and function of T regulatory cells (Treg) in the gut immune tissue and initiation and development of autoimmunity associated with type 1 diabetes (T1D).
Tamara Saksida, Verica Paunović, Ivan Koprivica, Dragica Mićanović, Bojan Jevtić, Natalija Jonić, Ivana Stojanović, Nada Pejnović   +7 more
doaj   +1 more source