Results 11 to 20 of about 697,637 (254)

Interleukin-2 and leukemia [PDF]

Leukemia, 1998
Leukemia has been treated with chemotherapy for the past 40 years with only moderate success. A growing body of evidence suggests that by augmenting the immune system more effective results may be obtained. This is highlighted by T cell reinfusions resulting in durable remissions in patients with chronic myelogenous leukemia who have relapsed after an ...
M, Goodman, L, Cabral, P, Cassileth
openaire   +2 more sources

Distinct Expression of Inflammatory Features in T Helper 17 Cells from Multiple Sclerosis Patients

Cells, 2019
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). T helper (Th) 17 lymphocytes play a role in the pathogenesis of MS.
Alessia Capone, Manuela Bianco, Gabriella Ruocco, Marco De Bardi, Luca Battistini, Serena Ruggieri, Claudio Gasperini, Diego Centonze, Claudio Sette, Elisabetta Volpe   +9 more
doaj   +1 more source

Interleukin-10 inhibits the production of inflammatory cytokines by antigen-stimulated mononuclear cells from asthmatic patients

Allergology International, 2000
Bronchial asthma, characterized by chronic airway inflammation, involves many inflammatory cytokines. Interleukin (IL)-10 is a potent inhibitor of cytokine synthesis.
Toshiya Takahashi, Ken-ichi Maeda, Yoichi Nakamura, Yoshio Okano, Ning Ge, Saburo Sone   +5 more
doaj   +1 more source

Treatment of refractory chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation with low-dose interleukin-2

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
Refractory chronic graft-versus-host disease (cGVHD) is the complication of allogeneic hematopoietic stem cell transplantation (HCT) that signi ficantly impacts quality of life, may be associated with morbidity and mortality and has limited treatment ...
I. S. Moiseev, E. A. Burmina, Y. A. Tarakanova, Y. R. Zalyalov, A. G. Smirnova, O. V. Pirogova, S. N. Bondarenko, B. V. Afanasyev   +7 more
doaj   +1 more source

Retrospective Analysis of Pediatric Hepatoblastoma With Tumor Rupture: Experience From a Single Center

Frontiers in Pediatrics, 2022
PurposeHepatoblastoma (HB) tumor rupture is currently considered as a high-risk factor in some risk stratification systems. This study aimed to investigate the value of HB tumor rupture in predicting the poor prognosis.MethodsThe clinical data from ...
Yu-Tong Zhang, Yu-Fei Zhao, Dian-Fei Yang, Jian Chang   +3 more
doaj   +1 more source

Expression of chicken interleukin-2 gene in Pichia methanolica

浙江大学学报. 农业与生命科学版, 2003
Chicken interleukin-2 (chIL-2) is an important cytokine discovered recently. To explore a new approach to the expression of chIL-2 gene in methyltrophic yeast-Pichia methanolica (P.
ZHOU Ji-yong, CHEN Ji-gang, WANG Jin-yong, ZHANG De-yong, ZHENG Xiao-juan   +4 more
doaj   +1 more source

Stress regulates the lymphocyte homing receptor CD62L (L-selectin) [PDF]

Arquivos de Neuro-Psiquiatria, 2003
Based on a previous study showing that panic disorder patients had increased expression of naïve phenotype lymphocytes (CD45RA+ and CD62L+), increased plasma cortisol, as well as decreased interleukin-2 (IL-2) producion, we hypothesized that changes in ...
Gisele Gus Manfro, Carlos Alexandre Netto, Mark Pollack, Kelin Maggioni Mezzomo, Frederic Preffer, Richard Kradin   +5 more
doaj   +1 more source

Elevations in Liver Transaminases in COVID-19: (How) Are They Related?

Frontiers in Medicine, 2021
Liver involvement in COVID-19 is not yet well-understood, but elevations in liver transaminases have been described to occur in 14–53% of the cases and are more frequently seen in severe disease.
Henrique Pott-Junior, Natália Queiroz Prado Bittencourt, Silvana F. G. Chacha, Rafael Luís Luporini, Rafael Luís Luporini, Marcia Regina Cominetti, Fernanda de Freitas Anibal, Fernanda de Freitas Anibal   +7 more
doaj   +1 more source

Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population

BMC Medical Genetics, 2020
Background Intervertebral disc degeneration (IVDD) is an age-related degenerative disease, presenting with low back pain or radicular pain. The inflammatory changes would occur in discs in the process of IVDD.
Sara Hanaei, Sina Abdollahzade, Maryam Sadr, Mohammad Hossein Mirbolouk, Ehsan Fattahi, Alireza Khoshnevisan, Nima Rezaei   +6 more
doaj   +1 more source

Better Identification of Cognitive Decline With Interleukin-2 Than With Amyloid and Tau Protein Biomarkers in Amnestic Mild Cognitive Impairment

Frontiers in Aging Neuroscience, 2021
The rate of cognitive decline among patients with amnestic mild cognitive impairment (aMCI) varies, and it is thus crucial to accurately predict the probability of cognitive deterioration in patients with MCI.
Chih-Sung Liang, Chih-Sung Liang, Chia-Lin Tsai, Guan-Yu Lin, Jiunn-Tay Lee, Yu-Kai Lin, Yu-Kai Lin, Che-Sheng Chu, Che-Sheng Chu, Yueh-Feng Sung, Chia-Kuang Tsai, Ta-Chuan Yeh, Hsuan-Te Chu, Ming-Wei Su, Fu-Chi Yang, Fu-Chi Yang   +15 more
doaj   +1 more source