Results 201 to 210 of about 97,446,967 (252)
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The Journal of Immunology, 1985
Abstract The role of interleukin 2 (IL 2) on the expression of IL 2 receptors and on the synthesis of gamma-interferon (gamma-IFN) by human thymocytes was investigated. Human thymocytes isolated from specimens obtained during cardiac surgery of infants and children were induced with one or all of the following agents: IL 2, concanavalin ...
G H, Reem, N H, Yeh
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Abstract The role of interleukin 2 (IL 2) on the expression of IL 2 receptors and on the synthesis of gamma-interferon (gamma-IFN) by human thymocytes was investigated. Human thymocytes isolated from specimens obtained during cardiac surgery of infants and children were induced with one or all of the following agents: IL 2, concanavalin ...
G H, Reem, N H, Yeh
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Annual Review of Immunology, 2008
Much data support an essential role for interleukin (IL)-2 in immune tolerance. This idea is much different from the early paradigm in which IL-2 is central for protective immune responses. This change in thinking occurred when a T regulatory cell defect was shown to be responsible for the lethal autoimmunity associated with IL-2/IL-2R deficiency. This
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Much data support an essential role for interleukin (IL)-2 in immune tolerance. This idea is much different from the early paradigm in which IL-2 is central for protective immune responses. This change in thinking occurred when a T regulatory cell defect was shown to be responsible for the lethal autoimmunity associated with IL-2/IL-2R deficiency. This
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Survey of Immunologic Research, 1984
Considerable progress has been made in the past year in clarifying the structure-function relationships that are central in controlling T lymphocyte proliferation. Once a cDNA probe for the IL-2 receptor is cloned, all the primary reagents needed for detailed study of the functional consequences of IL-2 binding will be available and one anticipates ...
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Considerable progress has been made in the past year in clarifying the structure-function relationships that are central in controlling T lymphocyte proliferation. Once a cDNA probe for the IL-2 receptor is cloned, all the primary reagents needed for detailed study of the functional consequences of IL-2 binding will be available and one anticipates ...
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Interleukin-2 and the interleukin-2 receptor complex
1990Abstract Interleukin 2 (IL-2), originally designated as a T cell growth factor, is a glycoprotein with a molecular weight of 15.4 kD. The genes encoding the human, murine, and bovine IL-2 were cloned, their nucleotide sequences determined, and corresponding amino acid sequences deduced.-3 Human IL-2 consists of 133 amino acids and ...
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Clinical and experimental immunology, 1987
PHA activated human peripheral blood mononuclear cells (MNC) were incubated with human interleukin 2 (IL-2) in the absence or in the presence of 10(-6)-10(-9) M hydrocortisone (HC). HC suppressed the proliferative response of the activated MNC to highly purified human leucocyte IL-2 in a dose dependent manner.
H J, Horst, H D, Flad
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PHA activated human peripheral blood mononuclear cells (MNC) were incubated with human interleukin 2 (IL-2) in the absence or in the presence of 10(-6)-10(-9) M hydrocortisone (HC). HC suppressed the proliferative response of the activated MNC to highly purified human leucocyte IL-2 in a dose dependent manner.
H J, Horst, H D, Flad
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Interleukins in cancer: from biology to therapy
Nature Reviews Cancer, 2021Peter Libby +2 more
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