Down‐regulation of BCL‐2 and its prevention by interleukin‐4 in cultured chronic lymphocytic leukaemia cells is a methodological artefact caused by failure of protein detection/extraction following the onset of cell death [PDF]
Aura S. Kamiguti +2 more
openalex +1 more source
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen +11 more
wiley +1 more source
Serum soluble interleukin-2 receptor levels in hairy cell leukaemia as a marker of tumour burden with prognostic value and as a tool for disease monitoring. [PDF]
Angotzi F +14 more
europepmc +1 more source
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
Histamine dihydrochloride and low-dose interleukin-2 in an emerging landscape of relapse prevention in acute myeloid leukemia. [PDF]
Nilsson MS +5 more
europepmc +1 more source
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge +21 more
wiley +1 more source
Interleukin-2 Receptor as a Marker of Oxidative Stress in Paediatric Patients with Chronic Kidney Disease or Hypertension. [PDF]
Marčun Varda N +5 more
europepmc +1 more source
Therapeutic interleukin-2 rewires skeletal-immune circuits to reverse postmenopausal bone loss
Pengcheng Zhou +9 more
openalex +1 more source

