Results 271 to 280 of about 23,125,138 (369)

Human recombinant interleukin-2 augments porcine natural killer cell cytotoxicity in vivo

, 1990
Kj Hennessy, F Blecha, Bw Fenwick, Rc Thaler, Jl Nelssen   +4 more
openalex   +1 more source

Interleukin‐2/anti‐interleukin‐2 monoclonal antibody immune complex suppresses collagen‐induced arthritis in mice by fortifying interleukin‐2/STAT5 signalling pathways

Immunology, 2012
Seon-Yeong Lee, M. Cho, H. Oh, J. Ryu, Min-jung Park, J. Jhun, Mi-Kyung Park, J. Stone, Ji‐hyun Ju, Sue‐Yun Hwang, Sung-Hwan Park, C. Surh, Ho‐Youn Kim   +12 more
semanticscholar   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Oncolytic adenovirus encoding variant interleukin-2 combined with chemotherapy enables PD-L1 inhibition in pancreatic cancer models. [PDF]

Cancer Immunol Immunother
Pakola SA, Ojala N, Kudling TV, Clubb JHA, Jirovec E, van der Heijden M, Arias V, Haybout L, Basnet S, Grönberg-Vähä-Koskela S, Quixabeira DCA, Santos JM, Cervera-Carrascon V, Hemminki O, Kanerva A, Mustonen H, Puolakkainen P, Seppänen H, Hemminki A.   +18 more
europepmc   +1 more source

Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit.

, 1993
Robert A. Kirken, Hallgeir Rui, Gerald A. Evans, William L. Farrar   +3 more
openalex   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy. [PDF]

Sci Adv
Yang K, Bai B, Li X, Rou W, Huang C, Lu M, Zhang X, Dong C, Qi S, Liu Z, Yu G.   +10 more
europepmc   +1 more source

Anti-Tac-H, a humanized antibody to the interleukin 2 receptor, prolongs primate cardiac allograft survival.

, 1991
Paul S. Brown, Gary L. Parenteau, Frederick M. Dirbas, Roger Garsia, C K Goldman, Maria A. Bukowski, Richard P. Junghans, Cary Queen, J Hakimi, W R Benjamin   +9 more
openalex   +2 more sources

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

[⁶⁸Ga]Ga-interleukin-2 for imaging activated T-lymphocytes: biochemical characterization and phase I study in normal subjects. [PDF]

Eur J Nucl Med Mol Imaging
Signore A, Galli F, Varani M, Campagna G, Bentivoglio V, Accardo A, Morelli G, Lauri C.   +7 more
europepmc   +1 more source