Results 201 to 210 of about 3,093,388 (334)
The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing
Advanced Materials, EarlyView.With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong +8 more
wiley +1 more source
MicroRNA regulation of CD8+ T cell responses. [PDF]
, 2019 MicroRNAs (miRNAs) are a class of short noncoding RNAs that play critical roles in the regulation of a broad range of biological processes. Like transcription factors, miRNAs exert their effects by modulating the expression of networks of genes that ...
Ansel, K Mark, Gagnon, John D
core +1 more source
Advanced Materials, EarlyView.Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu +10 more
wiley +1 more source
Interleukin (IL)-21 promotes intestinal IgA response to microbiota [PDF]
, 2015 Anthony Cao +5 more
openalex +1 more source
Data from Interleukin 21 Enhances Antibody-Mediated Tumor Rejection [PDF]
, 2023 Mark J. Smyth +8 more
openalex +1 more source
Advanced Materials, EarlyView.Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash +9 more
wiley +1 more source
Interleukin 21 in immunity and autoimmunity
, 2010 T cell help to B cells is a fundamental property of adaptive immunity, yet only recently have many of the cellular and molecular mechanisms of T cell help emerged. T follicular helper (Tfh) cells are the CD4+ T helper cells that provide cognate help to B cells for high affinity antibody production in germinal centres (GC).
openaire +2 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source