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The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor

2012
Interleukin (IL) 21 is a class I cytokine, which exerts pleiotropic effects on both innate and adaptive immune responses. It signals through a heterodimeric receptor complex consisting of the IL-21 receptor (IL-21R) and the common gamma chain (gC). A hallmark of the class I cytokine receptors is the class I cytokine receptor signature motif (WSXWS ...
Hamming, Ole Jensen   +8 more
openaire   +1 more source

Interleukins in cancer: from biology to therapy

Nature Reviews Cancer, 2021
Peter Libby   +2 more
exaly  

Interleukin 21

2016
Rosanne Spolski, Warren J. Leonard
openaire   +1 more source

Interleukin-21 Deficiency

2020
Robert P. Nelson, Javier Chinen
openaire   +1 more source

Immunobiology of Interleukin-21

2014
Cecile King, Helen McGuire
openaire   +1 more source

Interleukin-21 signaling

Reactome - a curated knowledgebase of biological pathways, 2017
openaire   +1 more source

gp130 AND THE INTERLEUKIN-6 FAMILY OF CYTOKINES

Annual Review of Immunology, 1997
Tadamitsu Kishimoto, Tetsuya Taga
exaly  

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

Nature Reviews Drug Discovery, 2012
Charles A. Dinarello, Anna Simon
exaly  

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod Dudakov, Alan M Hanash
exaly  

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