Results 1 to 10 of about 61,846,700 (305)

Peran Reseptor IL-21 (IL-21R) sebagai Target Terapi Pada Penyakit Arteri Perifer

open access: yesScripta Score Scientific Medical Journal, 2021
Background: Peripheral Artery Disease (PAD) is caused due to the disruption of blood supply to the periphery caused by blockages in the arteries. PAD is a disease that is difficult to detect and the current therapy is still limited to pharmacological ...
Muhammad Luthfi Adnan
doaj   +1 more source

Gene-Edited Interleukin CAR-T Cells Therapy in the Treatment of Malignancies: Present and Future

open access: yesFrontiers in Immunology, 2021
In recent years, chimeric antigen receptor T cells (CAR-T cells) have been faced with the problems of weak proliferation and poor persistence in the treatment of some malignancies.
Zhengchao Zhang   +9 more
doaj   +1 more source

Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

open access: yesNeural Regeneration Research, 2023
The noble gas argon has the potential to protect neuronal cells from cell death. So far, this effect has been studied in treatment after acute damage. Preconditioning using argon has not yet been investigated.
Stefanie Scheid   +5 more
doaj   +1 more source

Tonsillar Microbiome‐Derived Lantibiotics Induce Structural Changes of IL‐6 and IL‐21 Receptors and Modulate Host Immunity

open access: yesAdvanced Science, 2022
Emerging evidence emphasizes the functional impacts of host microbiome on the etiopathogenesis of autoimmune diseases, including rheumatoid arthritis (RA).
Jing Li   +29 more
doaj   +1 more source

TLR ligands induce antiviral responses in chicken macrophages. [PDF]

open access: yesPLoS ONE, 2014
Chicken macrophages express several receptors for recognition of pathogens, including Toll-like receptors (TLRs). TLRs bind to pathogen-associated molecular patterns (PAMPs) derived from bacterial or viral pathogens leading to the activation of ...
Neda Barjesteh   +5 more
doaj   +1 more source

Novel IL2RG Gene Mutation in One of Dizygotic Twins Causing Profound Changes of Receptor Structure

open access: yesFrontiers in Pediatrics, 2022
In this study, we report a 4-month-old boy with T−B+NK− severe combined immunodeficiency (SCID) due to a novel mutation in exon 2 of IL2RG, the gene encoding the interleukin (IL) common gamma chain (γc) of the cytokine receptors for IL-2, IL-4, IL-7, IL ...
Magdalena Rutkowska-Zapała   +6 more
doaj   +1 more source

A Possible Role for Nerve Growth Factor and Its Receptors in Human Sperm Pathology

open access: yesBiomedicines, 2023
Nerve growth factor (NGF) signalling affects spermatogenesis and mature sperm traits. In this paper, we aimed to evaluate the distribution and the role of NGF and its receptors (p75NTR and TrKA) on the reproductive apparatus (testis and epididymis) and ...
Anna Maria Stabile   +10 more
doaj   +1 more source

IL-21: The Future of Medicine [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Interleukin-21 (IL-21), a T- cell-derived cytokine, is a signaling molecule secreted by a subpopulation of T cells called follicular T helper (Tfh) cells.
Syed Raza Shah   +5 more
doaj   +1 more source

Association of a non-synonymous SNP of IL17RA gene with litter size traits in Large White and Landrace pigs

open access: yesVeterinary Integrative Sciences, 2021
Interleukin-17 receptor A (IL17RA) is one of the cytokine receptors of the pro-inflammatory interleukin-17 (IL17) cytokine family. The IL17 and IL17RA genes are involved in inflammatory and immune responses as well as reproductive process of ...
Worrarak Norseeda   +6 more
doaj   +1 more source

Case Report: Interleukin-2 Receptor Common Gamma Chain Defect Presented as a Hyper-IgE Syndrome

open access: yesFrontiers in Immunology, 2021
X-linked severe combined immunodeficiency (X-SCID) is caused by mutations of IL2RG, the gene encoding the interleukin common gamma chain (IL-2Rγ or γc) of cytokine receptors for interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21.
Brahim Belaid   +19 more
doaj   +1 more source

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