Results 111 to 120 of about 4,022,531 (291)

Assessment of T helper 17-associated cytokines in thromboangiitis obliterans

Journal of Inflammation Research, 2019
Shayan Keramat,1 Mohammad Hadi Sadeghian,1,2 Mohammad Reza Keramati,1,2 Bahare Fazeli3,4 1Hematology Department, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran; 2Pathology Department, Cancer Molecular Pathology ...
Keramat S, Sadeghian MH, Keramati MR, Fazeli B   +3 more
doaj  

Notch signaling contributes to liver inflammation by regulation of interleukin-22-producing cells in hepatitis B virus infection

Frontiers in Cellular and Infection Microbiology, 2016
The mechanism of hepatitis B virus (HBV) induced liver inflammation is not fully elucidated. Notch signaling augmented IL-22 secretion in CD4+ T cells, and Notch-IL-22 axis fine-tuned inflammatory response.
Xin Wei, Jiu-Ping Wang, Chun-Qiu Hao, Xiao-Fei Yang, Lin-Xu Wang, Chang-Xing Huang, Xue-Fan Bai, Jian-Qi Lian, Ye Zhang   +8 more
doaj   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

Arthritis Care &Research, EarlyView.
Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis.
Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman   +4 more
wiley   +1 more source

Role of Interleukin-22 in Tumor Angiogenesis [PDF]

, 2017
There is increasing recognition that the immune system plays a crucial role in either the promotion or inhibition of tumor development and growth. Current models of tumorigenesis rely on cells’ ability to evade the immune system. Escaping immune-mediated
Protopsaltis, Nicholas James
core  

Examining the role of salivary IL-2 and IL-22 in recurrent aphthous stomatitis: a diagnostic approach

Journal of Ideas in Health
Background: Recurrent aphthous stomatitis (RAS) is a prevalent inflammatory condition, that manifests as mouth ulcers. This study aims to evaluate IL-2 and IL-22 levels in saliva samples of individuals with recurrent aphthous stomatitis (RAS) compared ...
Mustafa Taher
doaj   +3 more sources

CD161+CD4+ T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and Interferon-gamma

Frontiers in Immunology, 2012
Hepatitis C virus infection is a major cause of chronic liver disease. CD4+ T cells play a key role in disease outcome. However, the critical functions and associated phenotypes of intrahepatic CD4+ T cells are not well defined.
Yu-Hoi eKang, Bianca eSeigel, Bertram eBengsch, Vicki eFleming, Eva eBillerbeck, Ruth eSimmons, Lucy eWalker, Chris eWillberg, Eleanor J Barnes, Anisha eBhagwanani, Ye eOo, Hubert eBlum, David eAdams, Robert eThimme, Paul eKlenerman   +14 more
doaj   +1 more source

Impact of Six‐Month Monitoring Compared to Three‐Month Monitoring of Laboratories During Methotrexate Therapy

Arthritis Care &Research, EarlyView.
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko, Ray Zhang, Sohini Mukherjee, Puneet Bajaj, Bonnie L. Bermas   +4 more
wiley   +1 more source

Interleukin‐22: friend or foe? [PDF]

Immunology & Cell Biology, 2019
Hasnain, Sumaira Z., Begun, Jakob
openaire   +4 more sources

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

Arthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang, Qai Ven Yap, Peter Pak Moon Cheung, Amelia Santosa, Gim Gee Teng   +4 more
wiley   +1 more source