Results 161 to 170 of about 4,022,531 (291)

Opportunities and challenges: interleukin-22 comprehensively regulates polycystic ovary syndrome from metabolic and immune aspects. [PDF]

open access: yesJ Ovarian Res, 2023
Geng Y   +11 more
europepmc   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

open access: yesAdvanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin   +8 more
wiley   +1 more source

Interleukin-17 und Interleukin-22: Schlüsselzytokine in der Gewebeentzündung

open access: yes, 2013
IL-17 and IL-22 are signature cytokines of T helper (Th) 17 and Th22 cells linking adaptive and innate immune responses via modulation of epithelial cell functions. The present thesis demonstrates that pro- and anti- inflammatory functions of Interleukin
Pennino, Davide
core  

Interleukin-22 and Interleukin-18 as Potential Blood Biomarkers in Dupilumab-Treated Atopic Dermatitis. [PDF]

open access: yesAllergy
Fukushima-Nomura A   +10 more
europepmc   +1 more source

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong   +4 more
wiley   +1 more source

Inhibition of Aryl hydrocarbon receptor Interleukin-22 signaling and worsening of intestinal inflammation by <i>Sutterella</i> species. [PDF]

open access: yesGut Microbes
Dupraz L   +18 more
europepmc   +1 more source

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