Results 41 to 50 of about 73,008,320 (286)
Cells, 2020 The interleukin-22 (IL-22) signaling pathway is well known to be involved in the progression of various cancer types but its role in bone metastatic breast cancer remains unclear.
Eun-Young Kim +5 more
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The Role of T Helper 22 Cells in Dermatological Disorders
Frontiers in Immunology, 2022 T helper 22 (Th22) cells are a newly identified subset of CD4+ T cells that secrete the effector cytokine interleukin 22 (IL-22) upon specific antigen stimulation, barely with IFN-γ or IL-17. Increasing studies have demonstrated that Th22 cells and IL-22
Yu Pan +12 more
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Research advances in understanding the role of interleukin-22 in renal disease
Linchuang shenzangbing zazhi, 2022 Interleukin 22（IL-22），a member of IL-10 cytokine superfamily，is dominantly produced by innate lymphoid cells and CD4+ T helper subtypes such as Th17 and Th22 cells.And interleukin-22 receptor （IL-22R） is a dimer composed of IL-22R1 and IL-10R2 subunit.IL-
Zhao Dan +7 more
doaj
Interleukin-22 in the pathogenesis and potential treatment of liver diseases
Liver Research, 2017 Interleukin (IL)-22, a member of the IL-10 cytokine family, plays critical roles in tissue repair and host defense. IL-22 binds to its hetereodimeric receptor (R) composed of IL-22R1 and IL-10R2 and activates downstream signaling, including Signal ...
Shi Yin, Dechun Feng
doaj +1 more source
Cell Reports Medicine, 2021 Summary: Necrotizing enterocolitis (NEC) is a deadly intestinal inflammatory disorder that primarily affects premature infants and lacks adequate therapeutics.
Belgacem Mihi +18 more
doaj +1 more source
International Journal of Dentistry and Oral Science, 2014 IL-22 is a cytokine that is assumed to improve anti-microbial defense of epidermal and epithelial cells and the cells of gas- trointestinal and respiratory systems. With respect to absence of enough relevant articles in this regard the aim of this study was to evaluate the correlation between IL-22 gene expression in gingival tissues as well as its ...
Amini Behbahani A +3 more
openaire +2 more sources
مجلة الكوفة الطبيةBackground: Interleukin-22 (IL-22) is an immunologically relevant cytokine in Crohn’s disease (CD), but its circulating clinical significance remains uncertain. This study evaluated serum IL-22 in Iraqi patients with CD and examined its association with
Ghaith Adnan Neamah +1 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba +29 more
wiley +1 more source
, 2003 Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B. +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source